Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1201-02-1

Post Buying Request

1201-02-1 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

1201-02-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1201-02-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,0 and 1 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1201-02:
(6*1)+(5*2)+(4*0)+(3*1)+(2*0)+(1*2)=21
21 % 10 = 1
So 1201-02-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H4F5N/c1-13-7-5(11)3(9)2(8)4(10)6(7)12/h13H,1H3

1201-02-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,3,4,5,6-pentafluoro-N-methylaniline

1.2 Other means of identification

Product number -
Other names Benzenamine,2,3,4,5,6-pentafluoro-N-methyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1201-02-1 SDS

1201-02-1Relevant articles and documents

Disubstitution on hexafluorobenzene with N-methylformamides

Koppang, R.,Grace, D.

, p. 27 - 30 (1994)

Nucleophilic attack on hexafluorobenzene by N-methylformamide, treated with different bases, gave N-methyl-2,3,4,5,6-pentafluoroformanilide, N-formyl-N,N'-dimethyl-2,3,5,6-tetrafluorophenylene-1,4-diamine and N,N'-diformyl-N,N'-dimethyl-2,3,5,6-tetrafluorophenylene-1,4-diamine.The substituted benzenes could be hydrolyzed to N-methyl-2,3,4,5,6-pentafluoroaniline and N,N'-dimethyl-2,3,5,6-tetrafluorophenylene-1,4-diamine.

Anilinic N-oxides support cytochrome P450-mediated N-dealkylation through hydrogen-atom transfer

Roberts, Kenneth M.,Jones, Jeffery P.

experimental part, p. 8096 - 8107 (2010/09/11)

The mechanism of N-dealkylation mediated by cytochrome P450 (P450) has long been studied and argued as either a single electron transfer (SET) or a hydrogen atom transfer (HAT) from the amine to the oxidant of the P450, the reputed iron-oxene. In our study, tertiary anilinic N-oxides were used as oxygen surrogates to directly generate a P450-mediated oxidant that is capable of N-dealkylating the dimethylaniline derived from oxygen donation. These surrogates were employed to probe the generated reactive oxygen species and the subsequent mechanism of N-dealkylation to distinguish between the HAT and SET mechanisms. In addition to the expected N-demethylation of the product aniline, 2,3,4,5,6-pentafluoro-N,N-dimethylaniline N-oxide (PFDMAO) was found to be capable of N-dealkylating both N,N-dimethylaniline (DMA) and N-cyclopropyl-N-methylaniline (CPMA). Rate comparisons of the N-demethylation of DMA supported by PFDMAO show a 27-fold faster rate than when supported by N,N-dimethylaniline N-oxide (DMAO). Whereas intermolecular kinetic isotope effects were masked, intramolecular measurements showed values reflective of those seen previously in DMAO- and the native NADPH/O2-supported systems (2.33 and 2.8 for the N-demethylation of PFDMA and DMA from the PFDMAO system, respectively). PFDMAO-supported N-dealkylation of CPMA led to the ring-intact product N-cyclopropylaniline (CPA), similar to that seen with the native system. The formation of CPA argues against a SET mechanism in favor of a P450-like HAT mechanism. We suggest that the similarity of KIEs, in addition to the formation of the ring-intact CPA, argues for a similar mechanism of Compound I (Cpd I) formation followed by HAT for N-dealkylation by the native and N-oxide-supported systems and demonstrate the ability of the N-oxide-generated oxidant to act as an accurate mimic of the native P450 oxidant.

Polyfluorinated arylnitramines

Platonov,Haas,Schelvis,Lieb,Dvornikova,Osina,Gatilov, Yu.V.

, p. 131 - 139 (2007/10/03)

N-methyl- and N-butylperfluoroarylamines are transformed by HNO3 into N-nitro-N-methyl- and N-nitro-N-butylperfluoroarylamines. These reactions were used to synthesise N-nitro-N-methylpentafluoroaniline and its p-CF3, -CN, -C6F5 substituted derivatives, N-nitro-N-methylperfluoro-2,4-xylidine, N-nitro-N-methyl-4-aminotetrafluoropyridine, N-nitro-N-methyl-5-aminoperfluoroindane, N-nitro-N-methyl-2-aminoheptafluoronaphthalene, 4,4′-bis(N-nitro-N-methylamino)octafluorobiphenyl from 4,4′-bis(N-methylamino)octafluorobiphenyl, N-nitro-N-n-butylpentafluoroaniline, N-nitro-N-n-butylperfluoro-p-toluidine, N-nitro-N-n-butyl-4-aminotetrafluoropyridine and N-nitro-bis(perfluoro-p-tolyl)amine. Tetrafluoro-p-benzoquinone and heptafluoro-p-toluquinol were obtained from N-methylpentafluoroaniline and N-methylperfluoro-p-toluidine, respectively, under the action of a mixture of HNO3 and H2SO4. The X-ray crystal structure of N-nitro-N-methylperfluoro-p-toluidine was determined.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1201-02-1