Disubstitution on hexafluorobenzene with N-methylformamides

Article abstract of DOI:10.1016/0022-1139(93)02903-R

Nucleophilic attack on hexafluorobenzene by N-methylformamide, treated with different bases, gave N-methyl-2,3,4,5,6-pentafluoroformanilide, N-formyl-N,N'-dimethyl-2,3,5,6-tetrafluorophenylene-1,4-diamine and N,N'-diformyl-N,N'-dimethyl-2,3,5,6-tetrafluorophenylene-1,4-diamine.The substituted benzenes could be hydrolyzed to N-methyl-2,3,4,5,6-pentafluoroaniline and N,N'-dimethyl-2,3,5,6-tetrafluorophenylene-1,4-diamine.