1201-06-5Relevant academic research and scientific papers
An Unusual O-Methylation in the Allan-Robinson Synthesis of Purpurascenin, a 3,5,6,7,8,2',4',5'-Octamethoxyflavone
Patwardhan, Sarita A.,Gupta, Amrit S.
, p. 3786 - 3795 (2007/10/02)
In the Allan-Robinson synthesis of 3,5,6,7,8,2',4',5'-octamethoxyflavone (Purpurascenin, I), from 2,4,6-trihydroxy-3,5,ω-trimethoxyacetophenone (IV) and asarylic anhydride, the expected intermediate, 5,7-dihydroxy-3,6,8,2',4',5'-hexamethoxyflavone (III) unusually gets further methylated to give 5-hydroxy-3,6,7,8,2',4',5'-heptamethoxyflavone (II) during the course of reaction.The possible mechanism of methylation is discussed.
Synthesis of Araneol and Araneosol, the Flavonoids of Anaphalis araneosa DC
Dutta, Pradeep K.,Bagchi, Debasis,Pakrashi, Satyesh C.
, p. 1037 - 1038 (2007/10/02)
Araneol (5,7-dihydroxy-3,6,8-trimethoxyflavone, I) and araneosol (5,7-dihydroxy-3,6,8,4'-tetramethoxyflavone, II) have been synthesised by Hoesch condensation of 1,3,5-trihydroxy-2,4-dimethoxybenzene (III) with methoxyacetonitrile, followed by Allan-Robin
