1201-24-7

Basic information

• Product Name: 5-Methyl-1H-indazole-3-carboxylic acid
• Synonyms: CHEMBRDG-BB 4006004;5-METHYL-1H-INDAZOLE-3-CARBOXYLIC ACID;5-METHYL-3-(1H)INDAZOLE CARBOXYLIC ACID;5-methyl-1H-indazole-3-carboxy;5-METHYLINDAZOLE-3-CARBOXYLIC ACID;1H-Indazole-3-carboxylic acid, 5-methyl-;5-methyl-1H-indazole-3-carboxylic acid(SALTDATA: H2O 0.1NaCl);1H-Indazole-5-Methyl-3-carboxylic acid, 97%
• CAS NO: 1201-24-7
• Molecular Formula: C₉H₈N₂O₂
• Molecular Weight: 176.17
• Product Categories: Indazole;API intermediates
• Mol File: 1201-24-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 343 °C
• Boiling Point: 443.27 °C at 760 mmHg
• Flash Point: 221.882 °C
• Appearance: /
• Density: 1.422 g/cm³
• Vapor Pressure: 1.23E-08mmHg at 25°C
• Refractive Index: 1.709
• Storage Temp.: 2-8°C
• PKA: 3.11±0.30(Predicted)
• CAS DataBase Reference: 5-Methyl-1H-indazole-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Methyl-1H-indazole-3-carboxylic acid(1201-24-7)
• EPA Substance Registry System: 5-Methyl-1H-indazole-3-carboxylic acid(1201-24-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 1201-24-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H8N2O2/c1-5-2-3-7-6(4-5)8(9(12)13)11-10-7/h2-4H,1H3,(H,10,11)(H,12,13)

Upstream product

• 1858-99-7 benzaldehyde p-tolylhydrazone 
• 100-52-7 benzaldehyde 
• 10501-70-9 1-benzylideneamino-5-methyl-indole-2,3-dione 
• 608-05-9 5-methyl-indole-2,3-dione 

Downstream Products

• 1448314-58-6 5-methyl-1-(3-methylbenzoyl)-1H-indazole-3-carboxylic acid ethyl ester 
• 1908-01-6 3-ethoxycarbonyl-5-methyl-1H-indazole 
• 660823-02-9 5-methyl-1H-indazole-3-carboxylic acid (4-fluorophenyl)amide 
• 1776-37-0 5-methyl-1H-indazole 
• 15719-64-9 methylammonium carbonate 

Relevant articles and documents

Synthetic method of 5-substituted indazole-3-carboxylic acid

The invention provides a synthesis method of 5-substituted indazole-3-carboxylic acid, and belongs to the field of pharmaceutical chemical synthesis, wherein R=hydrogen, alkyl, alkoxy, trifluoroalkoxyand halogen. A phenylhydrazine compound 3 is taken as a

Practical synthesis of 3-carboxyindazoles

A clean, high-yielding synthetic route to methyl 5-(bromomethyl)-1- tritylindazole 3-carboxylate 1 was needed. A principal intermediate was 5-methyl-3-carboxyindazole 2. An analysis of a by-product found after executing Schad's 3-carboxyindazole synthesis led to undertaking this reaction with an inverse addition in the principal step. This simple modification gave 2 in excellent and reproducible yields. Copyright Taylor & Francis, Inc.

Synthesis of some derivatives of 5 methylindazole 3 carboxylic acid

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