1202-08-0Relevant articles and documents
A convenient conversion of substituted cyclohexenones into aryl methyl ketones
Gehring, Andrep.,Bracher, Franz
, p. 2441 - 2447 (2012)
This work describes a straightforward multistep conversion of substrates containing a cyclohexenone moiety into mono-, bi- and tricyclic aryl methyl ketones in one single working process. Crucial steps are the addition of 1-ethoxyvinyllithium to the carbonyl group, followed by acid-catalyzed enol ether hydrolysis, dehydration, and dehydrogenation. Georg Thieme Verlag Stuttgart · New York.
Catalytic Friedel-Crafts acylation and benzoylation of aromatic compounds using activated hematite as a novel heterogeneous catalyst
Sharghi, Hashem,Jokar, Mahboubeh,Doroodmand, Mohammad Mahdi,Khalifeh, Reza
experimental part, p. 3031 - 3044 (2011/02/21)
Catalytic Friedel-Crafts acylation of benzene and unactivated benzenes such as chlorobenzene and nitrobenzene have been successfully carried out using activated hematite (α-Fe2O3) as a new, heterogeneous and green catalyst. Sonication of neat α-Fe2O3 in a water bath under air atmosphere at room temperature followed by heating at 200°C, dramatically increase the activity of α-Fe2O 3. With the catalyst loading as low as 5.0mol%, a wide variety of benzene derivatives were easily converted into the corresponding acylated products in a clean and high-yielding acylation reaction. It was found that the activated α-Fe2O3 could be efficiently recycled and reused several times by simple washing with ethyl acetate, this cannot be attained with most of the traditional catalysts. Copyright
Process for the production of isosolanone and solanone, intermediates useful in said process and organoleptic uses of said intermediates
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, (2008/06/13)
Described is a novel genus of compounds defined according to the structure: STR1 wherein Z represents hydrogen, MgX and the moiety having the structure: STR2 and X represents chlor, bromo, or iodo; as well as 5-isopropyl-8-methyl-5,8-nonadien-2-one; uses of same as intermediates in a process for producing isosolanone and solanone; and organoleptic uses of 5-isopropyl-8-methyl-5,8-nonadien-2-one and 2,6-dimethyl-5-methylene-1-hepten-4-ol. The novel process of our invention involved the steps of: (i) formation of the compound having the structure: STR3 by means of reacting 3-methyl-2-methylenebutanal with the compound having the structure: STR4 (ii) acid hydrolysis of the resulting compound in order to form 2,6-dimethyl-5-methylene-1-heptene-4-ol; (iii) reaction of 2,6-dimethyl-5-methylene-1-hepten-4-ol with methyl aceto acetate in order to form 2,6-dimethyl-5-methylene-1-hepten-4-yl aceto acetate or, directly, 5-isopropyl-8-methyl-5,8-nonadiene-2-one; (iv) reacting 2,6-dimethyl-5-methylene-1-hepten-4-yl aceto acetate in the presence of an appropriate catalyst to form the 5-isopropyl-8-methyl-5,8-nonadiene-2-one; and (v) isomerizing the 5-isopropyl-8-methyl-5,8-nonadien-2-one in order to form a mixture of solanone and the isosolanone or 5-isopropyl-8-methyl-5,8-nonadiene-2-one.
Some Novel Rearrangements of Monoterpenes with NBS/DMF Reagent
Agarwal, V. K.,Sethi, V. K.,Thappa, R. K.,Agarwal, S. G.,Dhar, K. L.
, p. 996 - 998 (2007/10/02)
Some novel oxidation products have been obtained during the reaction of citronellol (1), car-3-ene (5), 4-acetyl-car-2-ene and piperitone with N-bromosuccinimide in basic medium.Such products have not been reported earlier under the conditions used.
