120379-81-9

Basic information

• Product Name: 5-phenylethyl-imidazolidine-2,4-dione
• Synonyms: 5-phenylethyl-imidazolidine-2,4-dione
• CAS NO: 120379-81-9
• Molecular Weight: 204.228
• Mol File: 120379-81-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5-phenylethyl-imidazolidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-phenylethyl-imidazolidine-2,4-dione(120379-81-9)
• EPA Substance Registry System: 5-phenylethyl-imidazolidine-2,4-dione(120379-81-9)

Safety Data

• Hazardous Substances Data: 120379-81-9(Hazardous Substances Data)

Upstream product

• 104-53-0 3-phenyl-propionaldehyde 
• 151-50-8 potassium cyanide 
• 506-87-6 ammonium carbonate 
• 128429-56-1 2-amino-4-phenyl-butanenitrile 
• 124-38-9 carbon dioxide 
• 2038-57-5 3-Phenylpropan-1-amine 

Downstream Products

• 422511-02-2 N,N'-bis-tert-butyloxycarbonyl-5-phenylethyl-imidazolidine-2,4-dione 
• 85955-58-4 N²-<(S)-1-(ethoxycarbonyl)-3-phenylpropyl>-L-lysyl-L-proline 
• 121842-77-1 (R)-ethyl 2-bromo-4-phenylbutyrate 
• 121819-67-8 (R)-ethyl 2-chloro-4-phenylbutyrate 
• 121842-76-0 (R)-2-bromo-4-phenylbutyric acid 
• 121819-66-7 (R)-2-chloro-4-phenylbutanoic acid 
• 120095-49-0 N⁶-(tert-butoxycarbonyl)-N²-<(S)-1-(ethoxycarbonyl)-3-phenylpropyl>-L-lysyl-L-proline tert-butylester 
• 108428-39-3 N--L-alanyl>-L-proline tert butyl ester 
• 120292-59-3 N-<(R)-1-(ethoxycarbonyl)-3-phenylpropyl>-L-alaninyl-L-proline tert-butylester 
• 80828-38-2 N-<(S)-1-(ethoxycarbonyl)-3-phenylpropyl>-L-alanine tert-butylester 
• 80828-28-0 N-<(R)-1-(ethoxycarbonyl)-3-phenylpropyl>-L-alanine tert-butylester 
• 84324-12-9 N-<1(R)-(ethoxycarbonyl)-3-phenylpropyl>-(S)-alanine 
• 76547-98-3 Lisinopril 
• 75847-73-3 enalapril 

Relevant articles and documents

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Hydantoins are an important class of heterocycles with applications in pharmacy, agriculture, and as intermediates in organic synthesis. Traditional synthetic procedures to access hydantoins are target oriented with multiple synthetic steps and often use reagents that are not commercially available or sustainable. Herein, an efficient process is described for accessing hydantoins starting from commercially available amines using consecutive gas–liquid transformations (oxygen, carbon dioxide). This semi-continuous process produced ten benzylic/aliphatic hydantoins in good overall yields (52–84 %).

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