120381-42-2

Basic information

• Product Name: BenzenaMine, 5-fluoro-N-Methyl-2-nitro-
• Synonyms: BenzenaMine, 5-fluoro-N-Methyl-2-nitro-;5-fluoro-N-Methyl-2-nitroaniline;(5-Fluoro-2-nitro-phenyl)-methyl-amine
• CAS NO: 120381-42-2
• Molecular Formula: C₇H₇FN₂O₂
• Molecular Weight: 170.1410832
• Mol File: 120381-42-2.mol
• Article Data: 22

Chemical Properties

• Boiling Point: 282.8±30.0 °C(Predicted)
• Appearance: /
• Density: 1.361±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: -1.22±0.25(Predicted)
• CAS DataBase Reference: BenzenaMine, 5-fluoro-N-Methyl-2-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: BenzenaMine, 5-fluoro-N-Methyl-2-nitro-(120381-42-2)
• EPA Substance Registry System: BenzenaMine, 5-fluoro-N-Methyl-2-nitro-(120381-42-2)

Safety Data

• Hazardous Substances Data: 120381-42-2(Hazardous Substances Data)

Usage

Uses

5-Fluoro-N-methyl-2-nitroaniline acts as a reagent in the preparation of 2-aminobenzimidazoles as Raf kinase inhibitors. Synthesis and structure-activity relationship of novel, selective, orally bioavailable positive modulators of mGluR2.

Upstream product

• 446-35-5 2,4-Difluoronitrobenzene 
• 74-89-5 methylamine 
• 2369-11-1 5-fluoro-2-nitroaniline 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 1351413-47-2 N-methyl{4-[3-(methylamino)-4-nitro-phenoxy](2-pyridyl)}carboxamide 
• 1242328-88-6 3-({6-[(2-methoxypyridin-4-yl)oxy]-1H-benzimidazol-2-yl}methoxy)benzoic acid 
• 1242329-34-5 methyl 3-({6-[(2-methoxypyridin-4-yl)oxy]-1-methyl-1H-benzimidazol-2-yl}methoxy)benzoate 
• 1242329-33-4 methyl 3-[2-({4-[(2-methoxypyridin-4-yl)oxy]-2-(methylamino)phenyl}amino)-2-oxoethoxy]benzoate 

Relevant articles and documents

6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS

The present disclosure provides 6-heteroaryloxy benzimidazole and azabenzimidazole compounds and compositions thereof useful for inhibiting JAK2.

SUBSTITUTED PYRIDOINDOLES FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION

The present invention relates to novel compounds of formula (I) or (II), (I) or (II), wherein R1 to R6, R11 to R17 are as described herein, and their pharmaceutically acceptable salt thereof, and compositions including the compounds and methods of using the compounds.

FREE AMINO COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION

-84- ABSTRACT The present invention relates to novel compounds of formula (I), (I), wherein R1, R2, R3, R4, R5 and R6 are as described herein, and their pharmaceutically 5 acceptable salt, enantiomer or diastereomer thereof, and compositions including the