120398-89-2Relevant academic research and scientific papers
Nitroimidazole derivative and diagnostic imaging agent containing the same
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Page column 5; 6, (2011/07/06)
A nitroimidazole derivative represented by the following formula (1): [wherein R1represents a hydrogen atom or a C1-C4 alkanoyl group; and X represents a fluorine atom or an isotope thereof], and a diagnostic imaging agent containing the derivative as an active ingredient. The derivative enables imaging of the ischemic sites of a circulatory organ or imaging of cancer cells, and thus the derivative can provide information about the position and the amount of the ischemic sites or the cancer cells. Therefore, the derivative contributes to selection of appropriate treatment of ischemia or cancer.
Heterocyclic derivatives and radiosensitizing agents and antiviral agents comprising same as their active component
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, (2008/06/13)
A novel heterocyclic derivative of formula (I): STR1 wherein R1 represents STR2 and R2 represents hydrogen or acyl. When R2 is acyl, the derivative can be prepared, for example, by the following process: STR3 wherein R4 is acyl and R1 is STR4 The derivative is less toxic and has radiosensitizing activity and antiviral activity even at a low concentration. Radiosensitizing agents and antiviral agents containing the derivative as active component are also disclosed.
