120413-99-2Relevant academic research and scientific papers
A New and Simple Route to 3-Arylthiophenes
Sone, Tyo,Inoue, Manabu,Sato, Kazuaki
, p. 3779 - 3781 (1988)
3-Arylthiophenes were prepared from 2,5-dichlorothiophene in two steps. 2,5-Dichlorothiophene reacted regioselective with various aromatic compounds in the presence of AlCl3 under mild conditions to give 4-aryl-2-chlorothiophenes.The latter compounds were easily converted to the corresponding 3-arylthiophenes by catalytic dechloronation in good yields.
