120475-85-6Relevant academic research and scientific papers
Photoinduced DNA Interstrand Cross-Linking by Benzene Derivatives: Leaving Groups Determine the Efficiency of the Cross-Linker
Fan, Heli,Peng, Xiaohua
, p. 493 - 506 (2020/12/22)
We have synthesized and characterized two small libraries of 2-OMe or 2-NO2-benzene analogues 2a-i and 3a-i containing a wide variety of leaving groups. Irradiation of these compounds at 350 nm generated benzyl radicals that were spontaneously oxidized to
Mono and bis(bioreductive) alkylating agents: Synthesis and antitumor activities in a B16 melanoma model
Witiak,Loper,Ananthan,Almerico,Verhoef,Filppi
, p. 1636 - 1642 (2007/10/02)
Several potentially bis(alkylating) bis(quinones) (3-5) and 1,4- and 1,3-bis(alkylating) monoquinones (6-13) belonging to general structure 2,2'-ethylenebis[5-[(leaving group) methyl]-1,4-benzoquinone] (3-5) and 2,5- and 2,6-bis[(leaving group)methyl]-1,4
