1205-53-4

Basic information

• Product Name: Benzene, (2-nitro-1-pentenyl)-
• CAS NO: 1205-53-4
• Molecular Formula: C11H13NO2
• Molecular Weight: 191.23
• Mol File: 1205-53-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzene, (2-nitro-1-pentenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, (2-nitro-1-pentenyl)-(1205-53-4)
• EPA Substance Registry System: Benzene, (2-nitro-1-pentenyl)-(1205-53-4)

Safety Data

• Hazardous Substances Data: 1205-53-4(Hazardous Substances Data)

Upstream product

• 627-05-4 1-nitrobutane 
• 100-52-7 benzaldehyde 

Downstream Products

• 6683-92-7 1-phenylpentan-2-one 
• 110966-19-3 (2-nitro-pentyl)-benzene 
• 705-73-7 1-phenyl-2-pentanol 
• 876500-03-7 N-(1-benzyl-butyl)-propionamide 
• 119485-94-8 N-propyl-1-phenyl-2-pentylamine 
• 63951-01-9 RS-(+/-)-1-phenyl-2-aminopentane 

Relevant articles and documents

Hybrid dopamine uptake blocker-serotonin releaser ligands: A new twist on transporter-focused therapeutics

As part of our program to study neurotransmitter releasers, we report herein a class of hybrid dopamine reuptake inhibitors that display serotonin releasing activity. Hybrid compounds are interesting since they increase the design potential of transporter related compounds and hence represent a novel and unexplored strategy for therapeutic drug discovery. A series of N-alkylpropiophenones was synthesized and assessed for uptake inhibition and release activity using rat brain synaptosomes. Substitution on the aromatic ring yielded compounds that maintained hybrid activity, with the two disubstituted analogues (PAL-787 and PAL-820) having the most potent hybrid activity.