6683-92-7

Usage

Uses

Used in Pesticide Industry:
1-Phenyl-2-pentanone is used as a repellent in pesticides for its ability to deter honeybees from areas where the pesticides are applied. This application is crucial in protecting honeybee populations from the harmful effects of these chemicals, as honeybees play a vital role in pollination and maintaining the balance of ecosystems.
The use of 1-Phenyl-2-pentanone in pesticides aims to minimize the exposure of honeybees to toxic substances, thereby reducing the risk of colony collapse and promoting the health and sustainability of these essential pollinators. By incorporating this aryl ketone as a repellent, pesticide manufacturers can develop more environmentally friendly and honeybee-safe products that contribute to the preservation of these vital insects.

Synthesis Reference(s)

Chemistry Letters, 6, p. 1021, 1977Tetrahedron, 49, p. 7104, 1993 DOI: 10.1016/S0040-4020(01)87982-5

InChI:InChI=1/C11H14O/c1-2-6-11(12)9-10-7-4-3-5-8-10/h3-5,7-8H,2,6,9H2,1H3

Upstream product

• 65473-78-1 2-n-propyl-3-phenyloxirane 
• 5435-44-9 (E)-3-Ureido-but-2-enoic acid ethyl ester 
• 1205-53-4 1-phenyl-2-nitro-1-pentene 
• 858859-14-0 1-phenyl-1,2-dihydroxypentane 
• 855910-37-1 2-(4-chloro-phenyl)-3-oxo-hexanenitrile 
• 927-77-5 n-propylmagnesium bromide 
• 114-70-5 sodium phenylacetate 
• 141-75-3 butyryl chloride 
• 103-82-2 phenylacetic acid 
• 107-92-6 butyric acid 
• 103-80-0 phenylacetyl chloride 
• 705-73-7 1-phenyl-2-pentanol 
• 40911-68-0 (1-pentenyl-2-oxy)trimethylsilane 
• 110966-19-3 (2-nitro-pentyl)-benzene 

Downstream Products

• 41718-53-0 5-phenylnonan-4-one 
• 855211-49-3 3-benzyl-3-hydroxy-hexanoic acid ethyl ester 
• 16736-15-5 1-(p-Tolyl)-2-phenylhexen-⁽¹⁾-on-⁽³⁾ 
• 16736-10-0 1,2-Diphenyl-hexen-⁽¹⁾-on-⁽³⁾ 
• 16736-18-8 1-(p-Isopropylphenyl)-2-phenyl-hexen-⁽¹⁾-on-⁽³⁾ 
• 100368-82-9 2-Formamino-1-phenyl-pentan 
• 77989-11-8 3-propyl-4-phenyl-1,2,5-thiadiazole 
• 77989-10-7 3-o-bromophenyl-4-phenyl-1,2,5-thiadiazole 
• 77989-15-2 2-(4’,6’-diphenyl-1’,3’,5’-triazinyl)bromobenzene 
• 612825-00-0 4-benzyl-5-ethyl-2,6-bis-(4'-methoxyphenyl)-pyrimidine 
• 87923-50-0 ((R)-1-Benzyl-butyl)-((S)-1-phenyl-ethyl)-amine 
• 87923-49-7 (S,S)-(-)-N-(1-phenylethyl)-1-phenyl-2-aminopentane 
• 87923-47-5 (R,R)-(+)-N-(1-phenylethyl)-1-phenyl-2-aminopentane 

Relevant academic research and scientific papers

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Asymmetric Catalytic Epoxidation of Terminal Enones for the Synthesis of Triazole Antifungal Agents

An enantioselective epoxidation of α-substituted vinyl ketones was realized to construct the key epoxide intermediates for the synthesis of various triazole antifungal agents. The reaction proceeded efficiently in high yields with good enantioselectivities by employing a chiral N,N′-dioxide/ScIII complex as the chiral catalyst and 35% aq. H2O2 as the oxidant. It enabled the facile transformation for optically active isavuconazole, efinaconazole, and other potential antifungal agents.

Rhodium-Catalyzed Deoxygenation and Borylation of Ketones: A Combined Experimental and Theoretical Investigation

The rhodium-catalyzed deoxygenation and borylation of ketones with B2pin2 have been developed, leading to efficient formation of alkenes, vinylboronates, and vinyldiboronates. These reactions feature mild reaction conditions, a broad substrate scope, and excellent functional-group compatibility. Mechanistic studies support that the ketones initially undergo a Rh-catalyzed deoxygenation to give alkenes via boron enolate intermediates, and the subsequent Rh-catalyzed dehydrogenative borylation of alkenes leads to the formation of vinylboronates and diboration products, which is also supported by density functional theory calculations.

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Coupling of Sulfoxonium Ylides with Arynes: A Direct Synthesis of Pro-Chiral Aryl Ketosulfoxonium Ylides and Its Application in the Preparation of α-Aryl Ketones

A general, mild, and versatile synthesis of the challenging α-aryl-β-ketosulfoxonium ylides has been developed for the first time, substituting traditional methods starting from diazo compounds. The arylation of easily accessible β-ketosulfoxonium ylides using aryne chemistry allowed the preparation of a large scope of the pro-chiral ylides in very good yields (40 examples; up to 85%). As applications, these ylides were smoothly converted into α-aryl ketones after desulfurization in good yields (up to 98%) as well as in other important derivatives.

Carbonylative Coupling of Alkyl Zinc Reagents with Benzyl Bromides Catalyzed by a Nickel/NN2 Pincer Ligand Complex

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