705-73-7

Basic information

• Product Name: DL-1-phenylpentan-2-ol
• Synonyms: alpha-propylphenethyl alcohol;DL-1-phenylpentan-2-ol;1-Phenyl-2-pentanol;Benzeneethanol, .alpha.-propyl-;BENZYLPROPYLCARBINOL;.alpha.-propyl-Benzeneethanol;alpha-propyl-benzeneethano;(±)-α-Propylphenethyl alcohol
• CAS NO: 705-73-7
• Molecular Formula: C₁₁H₁₆O
• Molecular Weight: 164.24414
• EINECS: 211-887-0
• Product Categories: Aromatics, Heterocycles, Neurochemicals, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 705-73-7.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 251.3°C at 760 mmHg
• Flash Point: 105°C
• Appearance: /
• Density: 0.968g/cm³
• Vapor Pressure: 0.0108mmHg at 25°C
• Refractive Index: 1.515
• Solubility: Chloroform, DCM, Ethyl Acetate, Methanol
• PKA: 15.24±0.20(Predicted)
• CAS DataBase Reference: DL-1-phenylpentan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: DL-1-phenylpentan-2-ol(705-73-7)
• EPA Substance Registry System: DL-1-phenylpentan-2-ol(705-73-7)

Safety Data

• Hazardous Substances Data: 705-73-7(Hazardous Substances Data)

Usage

Chemical Properties

α-Propylphenethyl alcohol has a mild, green, sweet odor with an earthy undernote. It has a tart, fruit-like, green, sweet taste.

Occurrence

Reported found in Gruyere de Comte cheese.

Uses

2-Hydroxy-1-phenylpentane is an impurity of Prolintane (P756100) synthesis.

Preparation

From phenyl acetaldehyde and propyl magnesium bromide; also by hydrogenation of propyl benzyl ketone.

Synthesis Reference(s)

Tetrahedron Letters, 21, p. 2175, 1980 DOI: 10.1016/S0040-4039(00)78990-8

InChI:InChI=1/C11H16O/c1-2-6-11(12)9-10-7-4-3-5-8-10/h3-5,7-8,11-12H,2,6,9H2,1H3

Upstream product

• 6683-92-7 1-phenylpentan-2-one 
• 4436-24-2 1,2-epoxy-3-phenylpropane 
• 2397-68-4 sodium tetraethylaluminate 
• 100-44-7 benzyl chloride 
• 123-72-8 butyraldehyde 
• 134240-73-6 (R,S)-1-phenyl-2-pentyl acetate 
• 2234-82-4 1-propylmagnesium chloride 
• 122-78-1 phenylacetaldehyde 
• 100-52-7 benzaldehyde 
• 1205-53-4 1-phenyl-2-nitro-1-pentene 
• 97-93-8 triethylaluminum 
• 927-77-5 n-propylmagnesium bromide 
• 101-41-7 benzeneacetic acid methyl ester 
• 108-88-3 toluene 

Downstream Products

• 92925-72-9 2-Phenyl-hex-1-en-3-one 
• 100368-82-9 2-Formamino-1-phenyl-pentan 
• 63951-01-9 RS-(+/-)-1-phenyl-2-aminopentane 
• 188432-44-2 O-1-benzylbutyl S-methyl dithiocarbonate 
• 91787-11-0 1-benzylbutyl tosylate 
• 6683-92-7 1-phenylpentan-2-one 

Relevant articles and documents

Sulfonium ion-promoted traceless Schmidt reaction of alkyl azides

Schmidt reaction by sulfonium ions is described. General primary, secondary, and tertiary alkyl azides were converted to the corresponding carbonyl or imine compounds without any trace of the activators. This bond scission reaction through 1,2-migration of C-H and C-C bonds was accessible to the one-pot substitution reaction.

Coupling of Sulfoxonium Ylides with Arynes: A Direct Synthesis of Pro-Chiral Aryl Ketosulfoxonium Ylides and Its Application in the Preparation of α-Aryl Ketones

A general, mild, and versatile synthesis of the challenging α-aryl-β-ketosulfoxonium ylides has been developed for the first time, substituting traditional methods starting from diazo compounds. The arylation of easily accessible β-ketosulfoxonium ylides using aryne chemistry allowed the preparation of a large scope of the pro-chiral ylides in very good yields (40 examples; up to 85%). As applications, these ylides were smoothly converted into α-aryl ketones after desulfurization in good yields (up to 98%) as well as in other important derivatives.

Polynucleotides encoding enantioselective carboxylesterases and methods of making same

The present invention relates to a polynucleotide encoding an enzyme having carboxylesterase [E.C.3.1.1.1] activity.