1206975-97-4Relevant academic research and scientific papers
Synthetic study of matrine-type alkaloids: Stereoselective construction of the AB rings of the quinolizidine skeleton
Tsukano, Chihiro,Oimura, Atsuko,Enkhtaivan, Iderbat,Takemoto, Yoshiji
, p. 653 - 656 (2014)
A new method has been developed for the stereoselective construction of the AB rings of the quinolizidine skeleton of ?matrine-type alkaloids with a cis-cis stereochemistry. The key features of this method involve: (i)? construction of the quinolizidine by reduction of an acylpyridinium cation; and (ii)? late-stage introduction of methoxypyridine by sequential Stille coupling and diastereo?selective hydrogenation reactions. Georg Thieme Verlag Stuttgart. New York.
