120984-59-0

Basic information

• Product Name: tert-butyl 3-formylpropylmethylcarbamate
• Synonyms: tert-butyl 3-formylpropylmethylcarbamate
• CAS NO: 120984-59-0
• Molecular Formula: C₁₀H₁₉NO₃
• Molecular Weight: 201.26
• Mol File: 120984-59-0.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• CAS DataBase Reference: tert-butyl 3-formylpropylmethylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 3-formylpropylmethylcarbamate(120984-59-0)
• EPA Substance Registry System: tert-butyl 3-formylpropylmethylcarbamate(120984-59-0)

Safety Data

• Hazardous Substances Data: 120984-59-0(Hazardous Substances Data)

Upstream product

• 176686-14-9 [4-(tert-butyldimethylsilanyloxy)butyl]carbamic acid tert-butyl ester 
• 57294-38-9 N-(tert-butoxycarbonyl)-4-aminobutanoic acid 
• 123387-72-4 O-tert-butyl N-methyl-N-(2-oxoethyl)carbamate 
• 85275-45-2 N-tert-butoxycarbonyl-3-piperidinol 
• 143646-48-4 4-(tert-butoxycarbonylamino)butyraldehyde diethyl acetal 
• 108-88-3 toluene 
• 99207-32-6 4-(N-tert-Butyloxycarbonyl-N-methylamino)butanol 
• 94994-39-5 4-[(tert-butoxycarbonyl)(methyl)amino]butanoic acid 
• 761456-79-5 tert-butyl (4-(methoxy(methyl)amino)-4-oxobutyl)(methyl)carbamate 

Relevant articles and documents

Design, synthesis, and biological evaluation of cytotoxic 11-aminoalkenylindenoisoquinoline and 11-diaminoalkenylindenoisoquinoline topoisomerase I inhibitors

The cytotoxic indenoisoquinolines are a novel class of noncamptothecin topoisomerase I inhibitors having certain features that compare favorably with the camptothecins. A new strategy was adopted to attach aminoalkenyl substituents at C-11 of the indenoisoquinoline ring system, which, according to molecular modeling, would orient the side chains toward the DNA minor groove. All of the newly synthesized compounds were more cytotoxic than the parent indenoisoquinoline NSC 314622. Despite an imperfect correlation between cytotoxicities and topoisomerase I inhibition results, the hypothetical structural model of the cleavage complex presented here provides a conceptual framework to explain the structure-activity relationships.

MDM2 DEGRADERS AND USES THEREOF

The present invention relates to compounds and methods useful for the modulation of mouse double minute 2 homolog ("MDM2") protein via ubiquitination and/or degradation by compounds according to the present invention.

1,3-Alkyl Transposition in Allylic Alcohols Enabled by Proton-Coupled Electron Transfer

A method is described for the isomerization of acyclic allylic alcohols into β-functionalized ketones via 1,3-alkyl transposition. This reaction proceeds via light-driven proton-coupled electron transfer (PCET) activation of the O?H bond in the allylic al