121089-86-9Relevant articles and documents
Synthesis and contractile activity of substituted 1,2,3,4- tetrahydroisoquinolines
Ivanov, Iliyan,Nikolova, Stoyanka,Aladjov, Dimo,Stefanova, Iliyana,Zagorchev, Plamen
experimental part, p. 7019 - 7042 (2011/11/05)
A series of different 1-monosubstituted and 1,1-disubstituted 1,2,3,4-tetrahydroisoquinolines was synthesized in high yields from different ketoamides. We have developed a convenient method for the synthesis of disubstituted derivatives by interaction of
STUDIES ON FRIEDEL-CRAFTS ACYLATION OF N-ACETYLHOMOVERATRYLAMINE AND PREPARATION OF 1-SUBSTITUTED 3,4-DIHYDRO-6,7-DIMETHOXYISOQUINOLINES
Orito, Kazuhiko,Matsuzaki, Tsutomu,Suginome, Hiroshi,Rodrigo, Russel
, p. 2403 - 2412 (2007/10/02)
Friedel-Crafts acylation of N-acetylhomoveratrylamine in a molar ratio of 1:2:3 of 1, AlCl3 and the appropriate acid chloride using nitrobenzene as solvent gave the corresponding 2-acyl derivatives 2a-j in good yields.Subsequent treatment of 2 in boiling