10172-51-7

Basic information

• Product Name: 6,7-dimethoxy-1-phenyl-3,4-dihydroisoquinoline
• Synonyms: 6,7-dimethoxy-1-phenyl-3,4-dihydroisoquinoline
• CAS NO: 10172-51-7
• Molecular Formula: C₁₇H₁₇NO₂
• Molecular Weight: 267.32
• Mol File: 10172-51-7.mol
• Article Data: 42

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6,7-dimethoxy-1-phenyl-3,4-dihydroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-dimethoxy-1-phenyl-3,4-dihydroisoquinoline(10172-51-7)
• EPA Substance Registry System: 6,7-dimethoxy-1-phenyl-3,4-dihydroisoquinoline(10172-51-7)

Safety Data

• Hazardous Substances Data: 10172-51-7(Hazardous Substances Data)

Upstream product

• 744984-41-6 N-(3,4-dimethoxy-phenethyl)-benzamidine 
• 67616-16-4 N-[2-(3,4-dimethoxyphenyl)ethyl]benzamide 
• 4118-36-9 6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 65-85-0 benzoic acid 
• 22276-64-8 2-(6,7-dimethoxy-3,4-dihydroisoquinolin-1-yl)phenylamine 
• 100-52-7 benzaldehyde 
• 622-42-4 1-nitro-1-phenylmethane 
• 100-47-0 benzonitrile 
• 7417-21-2 2-(3,4-dimethoxyphenyl)ethyl alcohol 
• 98-88-4 benzoyl chloride 
• 23818-68-0 1,2,3,4-tetrahydro-6,7-dimethoxy-2-[(4-methylphenyl)sulfonyl]-1-phenylisoquinoline 
• 98215-75-9 6,7-dimethoxy-1-<(ortho-bromo)phenyl>-3,4-dihydroisoquinoline 
• 121089-86-9 N-(2-benzoyl-4,5-dimethoxyphenethyl)acetamide 

Downstream Products

• 52095-43-9 2-Ethenyl-4,5-dimethoxybenzophenon 
• 4029-09-8 6,7-dimethoxy-1-phenyl-isoquinoline 
• 1408083-17-9 C₁₉H₁₉NO₄ 
• 3316-80-1 6,7-dimethoxy-1-<(ortho-methoxy)phenyl>-3,4-dihydroisoquinoline 
• 1408083-30-6 C₁₉H₂₁NO₃ 
• 178032-64-9 (R)-(+)-6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline 
• 4118-36-9 6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline 
• 6075-62-3 6,7-dimethoxy-2-methyl-1-phenyl-3,4-dihydroisoquinolinium iodide 
• 18332-22-4 8,9-dimethoxy-10b-phenyl-6,10b-dihydro-5H-thiazolo[2,3-a]isoquinolin-3-one 
• 22604-04-2 (8,9-dimethoxy-2-oxo-10b-phenyl-6,10b-dihydro-5H-oxazolo[2,3-a]isoquinolin-3-ylidene)-acetic acid methyl ester 
• 128642-07-9 8,9-Dimethoxy-1,10b-diphenyl-1,5,6,10b-tetrahydro-[1,2,4]triazolo[3,4-a]isoquinoline-3-carboxylic acid ethyl ester 
• 128642-04-6 8,9-Dimethoxy-1,3,10b-triphenyl-1,5,6,10b-tetrahydro-[1,2,4]triazolo[3,4-a]isoquinoline 

Relevant articles and documents

Synthesis of 3,4-dihydroisoquinolines using nitroalkanes in polyphosphoric acid

A new method for the synthesis of 6,7-dimethoxy-3,4-dihydroisoquinoline based on the reaction of 2-(3,4-dimethoxyphenyl)ethan-1-amine (homoveratrylamine) with aliphatic nitro compounds in polyphosphoric acid (PPA) was developed.

Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes

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Ionic liquids-assisted synthesis of 3,4-dihydroisoquinolines by the Bishler-Napieralski reaction

The Bishler-Napieralski cyclodehydration of N-acyl-2-arylethylamines into the corresponding 3,4-dihydroisoquinolines with POCl3 as a dehydration reagent proceeds in ionic liquids under milder conditions and in higher yields.

Asymmetric Transfer Hydrogenation of Unhindered and Non-Electron-Rich 1-Aryl Dihydroisoquinolines with High Enantioselectivity

The use of arene/Ru/TsDPEN catalysts bearing a heterocyclic group on the TsDPEN in the asymmetric transfer hydrogenation (ATH) of dihydroisoquinolines (DHIQs) containing meta- or para-substituted aromatic groups at the 1-position results in the formation of products of high enantiomeric excess. Previously, only 1-(ortho-substituted)aryl DHIQs, or with an electron-rich fused ring gave products with high enantioselectivity; therefore, this approach solves a long-standing challenge for imine ATH.