121190-51-0

Basic information

• Product Name: O¹-p-nitrobenzyl-N²-benzyloxycarbonyl-L-2,6-diaminopimelic acid
• Synonyms: O¹-p-nitrobenzyl-N²-benzyloxycarbonyl-L-2,6-diaminopimelic acid
• CAS NO: 121190-51-0
• Molecular Weight: 459.456
• Mol File: 121190-51-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: O¹-p-nitrobenzyl-N²-benzyloxycarbonyl-L-2,6-diaminopimelic acid(CAS DataBase Reference)
• NIST Chemistry Reference: O¹-p-nitrobenzyl-N²-benzyloxycarbonyl-L-2,6-diaminopimelic acid(121190-51-0)
• EPA Substance Registry System: O¹-p-nitrobenzyl-N²-benzyloxycarbonyl-L-2,6-diaminopimelic acid(121190-51-0)

Safety Data

• Hazardous Substances Data: 121190-51-0(Hazardous Substances Data)

Upstream product

• 55254-25-6 L-2,6-dibenzyloxycarbonylaminopimelic acid mono p-nitrobenzyl ester 
• 41980-31-8 2,6-dicyanopiperidine 
• 41980-32-9 5,5'-trimethylenedihydantoin 
• 14289-34-0 (S,S)-2,6-diaminopimelic acid 
• 922-54-3 2,6-diaminopimelic acid 
• 42920-79-6 meso-2,6-dibenzyloxycarbonylaminopimelic acid 
• 123628-69-3 L-N,N-diphenyl-2,6-dibenzyloxycarbonylaminopimelamide 

Downstream Products

• 78082-26-5 N⁶-benzyloxycarbonyl-L-2,6-diaminopimelamic acid 
• 78057-80-4 N²-1-benzyl-N-(N-lauroyl-L-alanyl)-γ-D-glutamyl>-N⁶-benzyloxycarbonyl-L-2,6-diaminopimelamic acid 
• 78057-77-9 RP 56142 

Relevant articles and documents

Synthesis of RP 56142: a New Immunoactive Peptide

RP 56142, a new immunoactive peptide was synthesized on large scale (ca. 500 g) via L-2,6-diaminopimelic acid which was prepared by chemical or biochemical synthesis.The key derivative, N6-benzyloxycarbonyl-L-2,6-diaminopimelamic acid was synthesized by two methods.In the first, we used a copper chelate procedure.In the second, we selectively deblocked the amine at the α-position to the free carboxylic group by the N-carboxyanhydride method.Condensation of N6-benzyloxycarbonyl-L-2,6-diaminopimelamic acid and the appropriately protected lauroyl dipeptide and removal of the protecting groups afforded RP 56142.