55254-25-6

Basic information

• Product Name: L-2,6-dibenzyloxycarbonylaminopimelic acid mono p-nitrobenzyl ester
• Synonyms: L-2,6-dibenzyloxycarbonylaminopimelic acid mono p-nitrobenzyl ester
• CAS NO: 55254-25-6
• Molecular Weight: 593.59
• Mol File: 55254-25-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-2,6-dibenzyloxycarbonylaminopimelic acid mono p-nitrobenzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-2,6-dibenzyloxycarbonylaminopimelic acid mono p-nitrobenzyl ester(55254-25-6)
• EPA Substance Registry System: L-2,6-dibenzyloxycarbonylaminopimelic acid mono p-nitrobenzyl ester(55254-25-6)

Safety Data

• Hazardous Substances Data: 55254-25-6(Hazardous Substances Data)

Upstream product

• 14289-34-0 (S,S)-2,6-diaminopimelic acid 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 41980-31-8 2,6-dicyanopiperidine 
• 41980-32-9 5,5'-trimethylenedihydantoin 
• 123628-69-3 L-N,N-diphenyl-2,6-dibenzyloxycarbonylaminopimelamide 
• 42920-79-6 meso-2,6-dibenzyloxycarbonylaminopimelic acid 
• 922-54-3 2,6-diaminopimelic acid 

Downstream Products

• 121190-51-0 O¹-p-nitrobenzyl-N²-benzyloxycarbonyl-L-2,6-diaminopimelic acid 
• 78082-26-5 N⁶-benzyloxycarbonyl-L-2,6-diaminopimelamic acid 
• 78057-77-9 RP 56142 
• 78057-80-4 N²-1-benzyl-N-(N-lauroyl-L-alanyl)-γ-D-glutamyl>-N⁶-benzyloxycarbonyl-L-2,6-diaminopimelamic acid 

Relevant articles and documents

Synthesis of RP 56142: a New Immunoactive Peptide

RP 56142, a new immunoactive peptide was synthesized on large scale (ca. 500 g) via L-2,6-diaminopimelic acid which was prepared by chemical or biochemical synthesis.The key derivative, N6-benzyloxycarbonyl-L-2,6-diaminopimelamic acid was synthesized by two methods.In the first, we used a copper chelate procedure.In the second, we selectively deblocked the amine at the α-position to the free carboxylic group by the N-carboxyanhydride method.Condensation of N6-benzyloxycarbonyl-L-2,6-diaminopimelamic acid and the appropriately protected lauroyl dipeptide and removal of the protecting groups afforded RP 56142.