121194-93-2

Upstream product

• 100-39-0 benzyl bromide 
• 118464-50-9 6-O-tert-butyldimethylsilyl-2,3-O-isopropylidene-D-mannono-δ-lactam 

Downstream Products

• 121194-96-5 N-benzyl-4-O-benzyl-1,5-dideoxy-1,5-imino-2,3-O-isopropylidene-D-mannitol 
• 107244-34-8 6-epi-castanospermine 
• 121194-95-4 Methanesulfonate(3aR,8R,8aS,9R,9aR)-5-benzyl-9-benzyloxy-8-(tert-butyl-dimethyl-silanyloxy)-2,2-dimethyl-octahydro-[1,3]dioxolo[4,5-f]indolizin-5-ium; 
• 121194-95-4 Methanesulfonate(3aR,8S,8aS,9R,9aR)-5-benzyl-9-benzyloxy-8-(tert-butyl-dimethyl-silanyloxy)-2,2-dimethyl-octahydro-[1,3]dioxolo[4,5-f]indolizin-5-ium; 
• 121194-99-8 (3aR,6S,7R,7aR)-5-Benzyl-7-benzyloxy-2,2-dimethyl-hexahydro-[1,3]dioxolo[4,5-c]pyridine-6-carbaldehyde 
• 121195-01-5 N-benzyl-4-O-benzyl-1,5,7,8-tetradeoxy-1,5-imino-2,3-O-isopropylidene-DL-glycero-D-manno-oct-7-enitol 
• 121250-66-6 N-benzyl-4-O-benzyl-6-O-tert-butyldimethylsilyl-1,5,7-trideoxy-1,5-imino-2,3-O-isopropylidene-L-glycero-D-manno-octitol 
• 121194-97-6 N-benzyl-4-O-benzyl-6-O-tert-butyldimethylsilyl-1,5,7-trideoxy-1,5-imino-2,3-O-isopropylidene-D-glycero-D-manno-octitol 
• 121195-00-4 N-benzyl-4-O-benzyl-6-O-tert-butyldimethylsilyl-1,5,7,8-tetradeoxy-1,5-imino-2,3-O-isopropylidene-DL-glycero-D-manno-oct-7-enitol 

Relevant academic research and scientific papers

Synthesis of the enantiomers of 6-epicastanospermine and 1,6-diepicastanospermine from D- and L-gulonolactone.

The synthesis of the enantiomers of 6-epicastanospermine and of 1,6-diepicastanospermine from the enantiomeric gulonolactones is reported and the structure of the former is established as (1S,6R,7R,8R,8aR)-1,6,7,8-tetrahydroxyoctahydroindolizine. The inhibitory activities of the diastereomers against the amyloglucosidase-catalysed hydrolysis of p-nitrophenyl alpha-D-glucopyranoside were investigated, and the effects of 6-epicastanospermine and of 1,6-diepicastanospermine on 14 human liver glycosidases are reported.