121303-76-2 Usage
Uses
Used in Organic Synthesis:
ETHYL 3-METHYLAMINO-4,4,4-TRIFLUOROCROTONATE is used as a reagent in organic synthesis for its ability to participate in various chemical reactions, contributing to the formation of complex organic molecules.
Used in Pharmaceutical Research:
In pharmaceutical research, ETHYL 3-METHYLAMINO-4,4,4-TRIFLUOROCROTONATE is employed as an intermediate, playing a crucial role in the development of new pharmaceuticals due to its unique structural properties and reactivity.
Used in Agrochemical Development:
ETHYL 3-METHYLAMINO-4,4,4-TRIFLUOROCROTONATE is also utilized in the development of new agrochemicals, where its unique properties and reactivity are leveraged to create effective and innovative products for agricultural applications.
Check Digit Verification of cas no
The CAS Registry Mumber 121303-76-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,1,3,0 and 3 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 121303-76:
(8*1)+(7*2)+(6*1)+(5*3)+(4*0)+(3*3)+(2*7)+(1*6)=72
72 % 10 = 2
So 121303-76-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H10F3NO2/c1-3-13-6(12)4-5(11-2)7(8,9)10/h4,11H,3H2,1-2H3/b5-4-
121303-76-2Relevant academic research and scientific papers
METHOD FOR PRODUCING 3-AMINO-4,4,4-TRIFLUOROCROTONIC ACID ESTERS
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Page 7-9, (2010/11/30)
The invention relates to a method for producing 3-amino-4,4,4-trifluorocrotonic acid esters of formula (I) or their E/Z isomers or tautomeric forms, whereby R1 and R2, independent of one another, represent hydrogen, an optionally substituted linear C1-C4 alkyl radical or an optionally substituted benzyl radical, and R3 represents methyl or ethyl. The inventive method is characterized in that: a) an alkyl trifluoroacetate is reacted with an alkyl acetate of formula CH3-CO-OR3 and with an alkali metal alcoholate to form an enolate of a trifluoroacetoacetic acid ester of formula (II), whereby M represents sodium or potassium, and R3 has the aforementioned meaning, and afterwards; b) the alkali enolate of the trifluoroacetoacetic acid ester from step a) can, without further purification, directly react with an amine of formula NHR1R2 in the presence of an acid to form 3-amino-4,4,4-trifluorocrotonic acid esters. This two-step method enables the production of 3-amino-4,4,4- trifluorocrotonic acid esters in high yields without resulting in the formation of significant byproducts.
