1213236-33-9

Basic information

• Product Name: 1-(4-chlorophenyl)-3-methyl-1H-indazole
• Synonyms: 1-(4-chlorophenyl)-3-methyl-1H-indazole
• CAS NO: 1213236-33-9
• Molecular Weight: 242.708
• Mol File: 1213236-33-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-(4-chlorophenyl)-3-methyl-1H-indazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-chlorophenyl)-3-methyl-1H-indazole(1213236-33-9)
• EPA Substance Registry System: 1-(4-chlorophenyl)-3-methyl-1H-indazole(1213236-33-9)

Safety Data

• Hazardous Substances Data: 1213236-33-9(Hazardous Substances Data)

Upstream product

• 551-93-9 2-aminoacetophenone 
• 918163-19-6 1-(2-((4-chlorophenyl)amino)phenyl)ethanone 
• 637-87-6 1-Chloro-4-iodobenzene 
• 3176-62-3 3-methyl-1H-indazole 
• 2142-69-0 2-bromophenyl methyl ketone 
• 17473-76-6 N'-(4-chlorophenyl)benzohydrazide 
• 1246849-43-3 (E)-1-(2-(4-chlorophenylamino)phenyl)ethanone oxime 

Relevant articles and documents

Divergent strategy for the chemoselective synthesis of N-Arylbenzimidazoles and N-Arylindazoles from arylamino oximes

An efficient and divergent synthesis of N-arylbenzimidazoles and N-arylindazoles from arylamino oximes based on reaction conditions selection was developed. The synthesis was approached by treating oximes with BTC and the chemoselectivity was regulated by the amount of Et3N. This switchable N–N and N–C bond formation process features mild reaction conditions, simple execution, high chemoselectivity and broad substrate scope.

Assembly of N, N -disubstituted hydrazines and 1-aryl-1 H-indazoles via copper-catalyzed coupling reactions

CuI-catalyzed coupling of N-acyl-N′-substituted hydrazines with aryl iodides takes place at 60-90 °C to afford N-acyl-N′,N′- disubstituted hydrazines regioselectively and thereby gives a facile method for assembling N,N-diaryl hydrazines. N-Acyl-N′-substituted hydrazines can also react with 2-bromoarylcarbonylic compounds at 60-125 °C under the catalysis of CuI/4-hydroxy-l-proline to provide 1-aryl-1H-indazoles.

METHOD OF SYNTHESIZING 1H-INDAZOLE COMPOUNDS

A method is provided for synthesizing 1H-indazole compounds in which aromatic carbonyl compounds are reacted with a nitrogen source to form oximes which are then converted to 1H-indazoles.