121517-96-2Relevant academic research and scientific papers
Nucleic acid related compounds. 80. Synthesis of 5'-S-(alkyl and aryl)-5'-fluoro-5'-thioadenosines with Xenon difluoride or (diethylamido)sulfur trifluoride, hydrolysis in aqueous buffer, and inhibition of S-adenosyl-L-homocysteine hydrolase by derived 'a
Robins,Wnuk,Mullah,Dalley,Yuan,Lee,Borchardt
, p. 544 - 555 (2007/10/02)
Treatment of 5'-S-(alkyl and aryl)-5'-thioadenosine derivatives 2 with XeF2, or the corresponding sulfoxides 3 with DAST/SbCl3, gave diastereomeric 5'-fluoro compounds which were deprotected to give the 5'-S-(alkyl and aryl)-5'-fluor
Nucleic Acid Related Compounds. 76. Synthesis of 5'(E and Z)-Chloro-4',5'-didehydro-5'-deoxyadenosines via Chlorination and Thermolysis of Adenosine 5'-Sulfoxides. Mechanism-Based Inhibition of S-Adenosyl-L-homocysteine Hydrolase
Wnuk, Stanislaw F.,Dalley, N. Kent,Robins, Morris J.
, p. 111 - 117 (2007/10/02)
Treatment of 2',3'-di-O-acetyl-5'-S-(4-methoxyphenyl)-5'-thioadenosine (1a), or its sulfoxides 2a(SR) and 3a(SS), with iodobenzene dichloride and potassium carbonate in acetonitrile resulted in formation of the 5'-chloro(and 5',5'-di
