121876-96-8

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 4461-33-0 benzoyl isocyanate 
• 55-21-0 benzamide 
• 20353-93-9 <3-(dimethylamino)-2-azaprop-2-en-1-ylidene> dimethylammonium chloride 
• 344241-92-5 N,N-dimethylformamide dimethyl acetal 
• 102254-70-6 4-dimethylamino-2-phenyl-1-thia-3-aza-buta-1,3-diene 

Downstream Products

• 138371-13-8 N-benzoyliminoethylidenetriphenylphosphorane 
• 138371-12-7 bromure de 2-dimethylaminovinyltriphenylphosphonium 
• 55-21-0 benzamide 
• 119044-64-3 N-benzyl-N',N'-dimethylformamidine 
• 1313518-78-3 (R)-8-cyclopentyl-7-ethyl-5-methyl-2-(5-phenyl-1H-1,2,4-triazol-1-yl)-7,8-dihydropteridin-6(5H)-one 
• 1313518-99-8 (R)-7-ethyl-8-isopropyl-5-methyl-2-(5-phenyl-1H-1,2,4-triazol-1-yl)-7,8-dihydropteridin-6(5H)-one 
• 1371622-94-4 (R)-5-cyclopentyl-4-ethyl-7-(5-phenyl-1H-1,2,4-triazol-1-yl)-4,5-dihydro-[1,2,4]triazolo[4,3-f]pteridine 
• 1371622-95-5 (R)-5-cyclopentyl-4-ethyl-1-methyl-7-(5-phenyl-1H-1,2,4-triazol-1-yl)-4,5-dihydro-[1,2,4]triazolo[4,3-f]pteridine 
• 1371623-53-8 (R)-4-ethyl-5-isopropyl-7-(5-phenyl-1H-1,2,4-triazol-1-yl)-4,5-dihydro-[1,2,4]triazolo[4,3-f]pteridine 
• 4252-31-7 N-formylbenzamide 
• 100-42-5 styrene 
• 6343-54-0 N-benzylformamide 

Relevant academic research and scientific papers

PTERIDINONES AS INHIBITORS OF POLO - LIKE KINASE

The present invention provides compounds having a structure according to Formula (I) or a salt or solvate thereof, wherein ring A, X, R1, R2, R3, R4, R5 and R6, are defined herein. The invention further provides pharmaceutical compositions including the compounds of the invention and methods of making and using the compounds and compositions of the invention, e.g., in the treatment and prevention of various disorders, such as Parkinson's disease.

N-Thio- And N-selenophenacylaniidiries: Electrophilic activation as a route to some l-hetero-3-aza-4-dimethylaminobuta-l,3-dienes

The preparation of 2-phenyl-4-dimethylamino-l-aza-, 1-oxa-, 1-thia-, l-selena-3-azabuta-l,3-dienes as well as their 4-methyl derivatives is described following a new heteroatom interchange reaction process. Heteronucleophilic attack at one particular reactive site of bis-electrophilic amidinium salts is the key feature of the process. In addition, we also disclose that the substituted l-oxa-3-aza- and l,3-diazabuta-l,3-dienes can be obtained by a reactional transformation cascade initiated by either silver acetate addition or tosyl azide [3+2] cycloaddition onto the CS or CSe double bonds of the 1-thia- and l-selena-3-azabuta-l,3-diene analogues. The Royal Society of Chemistry 1999.