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(2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-carboxylic acid [1-(2-hydroxy-2-methylpropyl)-1H-pyrazol-3-yl]amide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1219084-26-0

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1219084-26-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1219084-26-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,9,0,8 and 4 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1219084-26:
(9*1)+(8*2)+(7*1)+(6*9)+(5*0)+(4*8)+(3*4)+(2*2)+(1*6)=140
140 % 10 = 0
So 1219084-26-0 is a valid CAS Registry Number.

1219084-26-0Downstream Products

1219084-26-0Relevant academic research and scientific papers

Discovery of RG7388, a potent and selective p53-MDM2 inhibitor in clinical development

Ding, Qingjie,Zhang, Zhuming,Liu, Jin-Jun,Jiang, Nan,Zhang, Jing,Ross, Tina M.,Chu, Xin-Jie,Bartkovitz, David,Podlaski, Frank,Janson, Cheryl,Tovar, Christian,Filipovic, Zoran M.,Higgins, Brian,Glenn, Kelli,Packman, Kathryn,Vassilev, Lyubomir T.,Graves, Bradford

supporting information, p. 5979 - 5983 (2013/08/23)

Restoration of p53 activity by inhibition of the p53-MDM2 interaction has been considered an attractive approach for cancer treatment. However, the hydrophobic protein-protein interaction surface represents a significant challenge for the development of s

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