1220106-80-8Relevant academic research and scientific papers
Rational design, synthesis and characterization of potent, drug-like monomeric Smac mimetics as pro-apoptotic anticancer agents
Bianchi, Aldo,Ugazzi, Marcello,Ferrante, Luca,Lecis, Daniele,Scavullo, Cinzia,Mastrangelo, Eloise,Seneci, Pierfausto
, p. 2204 - 2208 (2012/04/18)
A set of phenyl-substituted Smac mimetics/IAP inhibitor analogues of lead compound 2a was synthesized, aiming to retain its strong cell-free potency while increasing its bioavailability. Seventeen compounds 2b-r were prepared and characterized in vitro, u
