122166-76-1Relevant academic research and scientific papers
SUBSTITUTED PYRAZOLOAZEPIN-8-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS
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Page/Page column 50; 51, (2018/07/05)
The present invention relates to novel pyrazoloazepin-8-ones with phosphodiesterase inhibitory activity, as well as to their use as therapeutic agents in the treatment of inflammatory diseases and conditions.
MULTICYCLIC COMPOUNDS AND METHODS OF USING SAME
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Paragraph 00510, (2015/04/15)
The invention generally relates to compounds represented by Structural Formula I: or a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of
Nucleophilic Organosilicon Intermediates Turned Electrophilic:(Trimethylsilyl)metyl, Trimethylsilyloxy and also 2-Tetrahydropyranyloxy as Terminators of Cycloadditions of Allyl Cations. A Short Route to Dehydrozizaenes (6-Methylenetricyclo1,5>-undec-9,10-enes) and Related Tr...
Hoffman, H.M.R.,Eggert, Ulrike,Gibbels, Uwe,Giesel, Kunibert,Koch, Oskar,et al.
, p. 3899 - 3918 (2007/10/02)
A range of suitable precursors were synthesized in order to contrast and use Me3SiCH2-, Me3Sio- and THPO-groups as terminators in both inter- and intramolecular cycloadditions of allyl cations to cyclic 1,3-dienes.A variety of crowded bicyclic, and spirofused adducts with skeletons were obtained.The compounds are of interest, e.g., in perfumery.The work contributes to the development of carbocation-induced cyclization methodology.
