1222-42-0

Usage

General Description

2-[(2,3-Dimethylphenyl)amino]benzoic acid methyl ester is a chemical compound that is derived from benzoic acid and contains a methyl ester group. It is also known as methyl 2-[(2,3-dimethylphenyl)amino]benzoate. 2-[(2,3-Dimethylphenyl)amino]benzoic acid methyl ester is commonly used in the pharmaceutical industry as an intermediate in the synthesis of various organic compounds. It has potential applications in the production of medicines and drugs, as well as in research and development. The presence of the dimethylphenylamino group makes 2-[(2,3-Dimethylphenyl)amino]benzoic acid methyl ester a useful building block for the synthesis of a wide range of compounds with diverse properties and applications. Its chemical structure and properties make it an important and versatile compound in various chemical and pharmaceutical processes.

InChI:InChI=1/C16H17NO2/c1-11-7-6-10-14(12(11)2)17-15-9-5-4-8-13(15)16(18)19-3/h4-10,17H,1-3H3

Upstream product

• 67-56-1 methanol 
• 61-68-7 mefenamic Acid 
• 74-88-4 methyl iodide 

Downstream Products

• 13481-66-8 N-<2,3-Dimethyl-phenyl>-anthranilsaeure-amid 
• 22121-60-4 2-((2,3-dimethylphenyl)amino)benzohydrazide 
• 1804-52-0 (2-((2,3-dimethylphenyl)amino)phenyl)methanol 

Relevant academic research and scientific papers

Synthesis and evaluation of some new hydrazones as corrosion inhibitors for mild steel in acidic media

Mild steel corrosion in HCl solution is an example of corrosion in acidic mediums. The ongoing research efforts to develop novel environmentally friendly corrosion inhibitors raise questions regarding their ability to effectively protect steel from corros

Synthesis, crystal structure, Hirshfeld surface analysis and DFT calculations of 2-[(2,3-dimethylphenyl)amino]-N’-[(E)-thiophen-2-ylmethylidene]benzohydrazide

Hydrazones are an important class of organic compounds, which exhibit large pharmacological applications. Hydrazones have long been used for the synthesis of a wide range of useful heterocyclic compounds due to their reactivity toward electrophiles and nu

Synthesis, experimental and theoretical characterization of (E)-2-((2,3-dimethylphenyl)amino)-N’-(furan-2-ylmethylene)benzohydrazide

Hydrazone derivatives have drawn much attention because of their large pharmacological applications. In the present work, the compound (E)-2-((2,3-dimethylphenyl)amino)-N’-(furan-2-ylmethylene)benzohydrazide, noted C20H19N3/sub

Microwave-assisted one-step synthesis of fenamic acid hydrazides from the corresponding acids

A facile and efficient method for synthesis of fenamic acid hydrazides from their acids in one-step reaction under microwave irradiation and solvent-free conditions was developed. Compared with the two-step conventional heating method, the process was simple, the reaction time was very short and the yields were almost quantitative.

Synthesis, analgesic and anti-inflammatory activities of chalconyl-incorporated hydrazone derivatives of mefenamic acid

A series of chalconyl-incorporated hydrazone derivatives of mefenamic acid was synthesized in order to obtain new compounds with potential analgesic and anti-inflammatory activity having lesser side effects. The structures of all synthesized compounds were confirmed by means of elemental analysis, IR, 1H NMR, 13C NMR and mass spectra. All compounds were evaluated for their analgesic and anti-inflammatory activities by tail-flick method and carrageenan-induced rat paw edema test, respectively. Among all the synthesized compounds, compounds (4a) and (4j) exhibited the most prominent and consistent anti-inflammatory activity. In acute ulcerogenicity study, it can be concluded that compounds (4a) and (4j) are devoid of the deadlier gastrointestinal toxicities.

Design and synthesis of 1-aroyl-2-ylidene hydrazines under conventional and microwave irradiation conditions and their cytotoxic activities

We report the design and synthesis of 1-aroyl-2-(alkenyl/aryl)idene hydrazines as hybrid molecules derived from mefenamic acid and substituted hydrazones. A number of compounds based on this new scaffold were prepared in good yields. The key intermediate

New esters of N arylanthranilic acids

A series of acyloxy and alkyloxymethyl esters of meclofenamic, flufenamic and mefenamic acids has been synthesized and its antiinflammatory, analgesic and antipyretic activities have been compared with those of the corresponding acids and the methyl, β,γ isopropylidenedioxypropyl, and N,N diethylaminoethyl esters. The acyloxy and alkyloxymethyl esters are the most interesting compounds, because they possess pharmacological activity of the same order as that of the corresponding acids and a lower toxicity. The ethoxymethyl ester of N (2,6 dichloro m tolyl)anthranilic acid is presently under clinical investigation.