1223047-89-9

Upstream product

• 5216-31-9 1,2-bis(4-fluorophenyl)acetylene 
• 100-58-3 phenylmagnesium bromide 
• 766-98-3 1-ethynyl-4-fluorobenzene 
• 352-34-1 4-fluoro-1-iodobenzene 
• 591-51-5 phenyllithium 
• 536-74-3 phenylacetylene 
• 150177-33-6 (Z)-(1-phenylethene-1,2-diyl)bis(trimethylgermane) 
• 873-55-2 sodium benzenesulfonate 

Relevant academic research and scientific papers

Synthesis of vinylgermanes via the Au/TiO2-catalyzed cis-1,2-digermylation of alkynes and the regioselective hydrogermylation of allenes

In the presence of Au/TiO2 (1 mol %), terminal alkynes react quantitatively with stoichiometric amounts of the unactivated digermane Me3Ge-GeMe3, forming exclusively cis-1,2-digermylated alkenes. We also establish the Au/TiO2-catalyzed hydrogermylation of terminal allenes with Et3GeH, which exhibits a highly regioselective mode of addition on the more substituted double bond forming vinylgermanes. Additionally, we provide preliminary results regarding the Pd nanoparticle-catalyzed C-C coupling of 1,2-digermyl alkenes with aryl iodides.

Zirconoarylation of alkynes through p-chloranilpromoted reductive elimination of arylzirconates

A novel method for the zirconoarylation of alkynes was developed. TCQ-promoted reductive elimination of arylzirconate [LiCp2ZrAr(RC=CR) ], which was prepared by the reaction of zirconocene-alkyne complexes with aryllithium compounds, afforded trisubstituted alkenylzirconocenes. This reaction can afford multi-substituted olefins with high stereoselectivity.

Ambient arylmagnesiation of alkynes catalysed by ligandless nickel(ii)

A simple and efficient catalytic arylmagnesiation of diarylacetylenes and aryl(alkyl)acetylenes is accomplished by NiCl2·6H2O at r.t. in the absence of stabilising ligands. The corresponding tetra-substituted alkenes can be obtained in good yields by subsequent treatment with different electrophiles. The Royal Society of Chemistry 2013.

Palladium-catalyzed desulfitative hydroarylation of alkynes with sodium sulfinates

A palladium-catalyzed desulfitative hydroarylation of alkynes with aryl sulfinic acid sodium salts is described. The reaction showed good regio- and stereoselectivity, and afforded the hydroarylation products in good yields. Various functional groups were well tolerated under the optimized reaction conditions.