412334-35-1

Upstream product

• 2645-02-5 methyl tosylglycinate 
• 118892-74-3 3-hydroxymethyl-pyridine-2-carboxylic acid isopropyl ester 
• 699-98-9 Pyridine-2,3-dicarboxylic anhydride 
• 118892-73-2 2,3-pyridinedicarboxylic acid 2-(isopropyl ester) 
• 142777-96-6 isopropyl 3-(chlorocarbonyl)pyridine-2-carboxylate 

Downstream Products

• 410542-68-6 8-hydroxy-1,6-naphthyridine-7-carboxylic acid methyl ester 
• 1422434-85-2 C₁₅H₁₆BrN₃O₂ 
• 1223081-81-9 5-bromo-8-(((1r,4r)-4-((tert-butoxycarbonyl)amino)cyclohexyl)amino)-1,6-naphthyridine-7-carboxylic acid 
• 1223081-79-5 tert-butyl(1r,4r)-4-(7-(methoxycarbonyl)-5-bromo-1,6-naphthyridin-8-amino)cyclohexyl carbamate 
• 1223081-70-6 methyl 5-bromo-8-((4-fluorobenzyl)amino)-1,6-naphthyridine-7-carboxylate 
• 410545-60-7 methyl 5-bromo-8-p-toluenesulfonyloxy-1,6-naphthyridine-7-carboxylate 
• 1407998-56-4 5-bromo-7-(cyclohexylcarbamoyl)-1,6-naphthyridin-8-yl 4-methylbenzenesulfonate 
• 1407998-55-3 5-bromo-8-hydroxy-N-cyclohexyl-1,6-naphthyridine-7-carboxamide 

Relevant academic research and scientific papers

Three substituted naphthyridine compounds and its preparation and use

The invention relates to 1,3,5-tri-substituted-1H-imidazo[4,5-h]1,6-diazanaphthalene-2(3H)-one compounds shown as the general formula I, isomers thereof and pharmaceutically acceptable salts thereof, a preparation method and applications thereof, and comp

Repositioning HIV-1 integrase inhibitors for cancer therapeutics: 1,6-naphthyridine-7-carboxamide as a promising scaffold with drug-like properties

Among a large number of HIV-1 integrase (IN) inhibitors, the 8-hydroxy-[1,6]naphthyridines (i.e., L-870,810) were one of the promising class of antiretroviral drugs developed by Merck Laboratories. In spite of its remarkable potency and efficacy, unfortun