1225322-48-4Relevant academic research and scientific papers
Visible-light induced decarboxylative alkylation of quinoxalin-2(1H)-ones at the C3-position
Xue, Wenxuan,Su, Yingpeng,Wang, Ke-Hu,Zhang, Rong,Feng, Yawei,Cao, Lindan,Huang, Dangfeng,Hu, Yulai
, p. 6654 - 6661 (2019)
A simple and efficient method for the visible light induced direct carbon alkylation of quinoxalin-2(1H)-ones at the C3 position is described. This protocol employs cheap and readily available phenyliodine(iii) dicarboxylates as the alkylation reagents to conduct decarboxylative radical coupling reaction with quinoxalin-2(1H)-ones. The process exhibits excellent compatibility to functional groups and provides a convenient and selective access to various 3-alkylquinoxalin-2(1H)-ones in good yields.
Peroxide-mediated site-specific C-H methylation of imidazo[1,2-: A] pyridines and quinoxalin-2(1 H)-ones under metal-free conditions
Jin, Shengzhou,Yao, Hua,Lin, Sen,You, Xiaoqing,Yang, Yao,Yan, Zhaohua
supporting information, p. 205 - 210 (2020/01/13)
An effective approach to realize the direct methylation of imidazo[1,2-a]pyridines and quinoxalin-2(1H)-ones with peroxides under metal-free conditions is described. In this protocol, peroxides serve as both the radical initiator and methyl source. Methylated imidazopyridines and quinoxalin-2(1H)-ones were smoothly synthesized in moderate to good yields. A free radical reaction mechanism was proposed to describe the methylation process.
