122590-93-6

Basic information

• Product Name: Benzene, [[difluoro(phenylsulfonyl)methyl]thio]-
• CAS NO: 122590-93-6
• Molecular Formula: C13H10F2O2S2
• Molecular Weight: 300.35
• Mol File: 122590-93-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzene, [[difluoro(phenylsulfonyl)methyl]thio]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, [[difluoro(phenylsulfonyl)methyl]thio]-(122590-93-6)
• EPA Substance Registry System: Benzene, [[difluoro(phenylsulfonyl)methyl]thio]-(122590-93-6)

Safety Data

• Hazardous Substances Data: 122590-93-6(Hazardous Substances Data)

Upstream product

• 1535-65-5 difluoromethyl phenyl sulfone 
• 882-33-7 diphenyldisulfane 
• 1535-67-7 difluoromethyl phenyl sulfide 
• 1052174-67-0 C₁₆H₁₅F₂IO₃S 
• 108-98-5 thiophenol 
• 873-55-2 sodium benzenesulfonate 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 75-45-6 Chlorodifluoromethane 

Downstream Products

• 122590-94-7 1,1-difluoro-1,1-bis(phenylsulfonyl)methane 

Relevant articles and documents

Electrophilic (phenylsulfonyl)difluoromethylation of thiols with a hypervalent iodine(III)-CF2SO2Ph reagent

A hypervalent iodine(III)-CF2SO2Ph compound (3) has been successfully prepared with selective nucleophilic reaction using PhSO2CF2SiMe3 reagent, and this previously unkown compound 3 was found to act as a new electrophilic (phenylsulfonyl)difluoromethylation reagent for a variety of S-nucleophiles under very mild reaction conditions.

NUCLEOPHILIC ADDITION OF DIFLUOROMETHYL PHENYL SULFONE TO ALDEHYDES AND VARIOUS TRANSFORMATIONS OF THE RESULTING ALCOHOLS

Nucleophilic addition of difluoromethyl phenyl sulfone (1) to various aldehydes occured in a two phase system ( 50 percent aqueous sodium hydroxide, dichloromathane, Aliquat 336 ) to give difluoro(phenylsulfonyl)methyl substituted alcohols (2-8).The product alcohol derived from para-tolualdehyde was converted to the difluoromethylated alcohol by desulfonylation and to the α, β, β-trifluorostyrene by a fluorination-elimination sequence.In the absence of aldehydes, 1 reacted in two phase system to give difluoro(phenylsulfonyl)methyl phenyl sulfide (9).The pathway of the latter conversion was studied.