1226-64-8

Usage

Uses

Used in Pharmaceutical Research:
1,3-bis(2-methoxyphenyl)thiourea is used as a pharmaceutical candidate for its potential antitumor properties, making it a subject of interest in cancer research. It is studied for its ability to inhibit the growth of certain types of tumors, offering a potential avenue for the development of new cancer treatments.
Used in Antithyroid Applications:
1,3-bis(2-methoxyphenyl)thiourea is also used as an antithyroid agent, indicating its potential role in the treatment of thyroid-related disorders by interfering with the synthesis of thyroid hormones.
Used in Corrosion Inhibition:
1,3-bis(2-methoxyphenyl)thiourea is used as a corrosion inhibitor for metal surfaces, providing protection against the damaging effects of corrosive substances and extending the lifespan of metal components in various industries.
Used in Organic Synthesis:
As a reagent in organic chemistry, 1,3-bis(2-methoxyphenyl)thiourea is used in the synthesis of a variety of organic compounds, contributing to the development of new chemical products and materials.
Used in Research and Development:
In the field of research and development, 1,3-bis(2-methoxyphenyl)thiourea is utilized for its potential applications in various scientific and industrial processes, including the development of new materials and the study of chemical reactions.

Upstream product

• 90-04-0 2-methoxy-phenylamine 
• 3288-04-8 1-isothiocyanato-2-methoxybenzene 
• 119650-93-0 N-(o-methoxyphenyl)-As,As-di-p-tolylarsinous amide 
• 17356-08-0 thiourea 
• 333-20-0 potassium thioacyanate 
• 91-23-6 2-Nitroanisole 
• 534-18-9 sodium trithiocarbonate 
• 75-15-0 carbon disulfide 
• 1147550-11-5 ammonium thiocyanate 

Downstream Products

• 85788-85-8 1,3-bis-(2-methoxy-phenyl)-2-thio-barbituric acid 
• 23233-42-3 3-N-(2-methoxyphenyl),2-N'-(2-methoxyphenyl)iminothiazolidin-4-one 
• 248279-10-9 N,N'-bis-(2-methoxy-phenyl)-S-methyl-isothiourea 
• 32826-86-1 3-(2-methoxy-phenyl)-thiazolidine-2,4-dione 
• 36220-38-9 (2-methoxy-phenyl)-[3-(2-methoxy-phenyl)-4-phenyl-3H-thiazol-2-ylidene]-amine 
• 42748-49-2 (2-methoxy-phenyl)-[3-(2-methoxy-phenyl)-4-methyl-3H-thiazol-2-ylidene]-amine 
• 36220-69-6 4-[3-(2-methoxy-phenyl)-2-(2-methoxy-phenylimino)-2,3-dihydro-thiazol-4-yl]-phenol 
• 82686-71-3 [4-Isopropyl-3-(2-methoxy-phenyl)-3H-thiazol-(2Z)-ylidene]-(2-methoxy-phenyl)-amine 
• 79051-77-7 2-(o-methoxyphenylimino)-3-(o-methoxyphenyl)-4-(isobutyl)-Δ4-thiazoline 
• 82694-14-2 [5-Ethyl-3-(2-methoxy-phenyl)-4-methyl-3H-thiazol-(2Z)-ylidene]-(2-methoxy-phenyl)-amine 
• 130255-89-9 4-(o-Methoxyphenyl)-5-(o-methoxyphenylimino)-1,2,4-dithiazolidin-3-on 
• 130749-44-9 6-amino-1,3-di(2-methoxybenzene)-2-thiouracil 
• 79051-21-1 2-(o-methoxyphenylimino)-3-(o-methoxyphenyl)-4-(p-tolyl)-Δ4-thiazoline 
• 82694-30-2 [4-Ethyl-3-(2-methoxy-phenyl)-5-methyl-3H-thiazol-(2Z)-ylidene]-(2-methoxy-phenyl)-amine 

Relevant academic research and scientific papers

Alkaline earth metal complexes stabilized by amidine and guanidine ligands: Synthesis, structure and their catalytic activity towards polymerization of: Rac-lactide

A series of amidine ligands RAmDIPP (R is backbone substituent, R = 2-methylpyridine (HL1), N,N,2-trimethylaniline (HL2), N,N-dimethylpropan-1-amine (HL3); DIPP (2,6-diisopropylphenyl) is N substituent) and a (Z

A facile method for the preparation of carbodiimides from thioureas and (Boc)2O

A concise method for the preparation of carbodiimides from thioureas using di-tert-butyl dicarbonate [(Boc)2O] as the dehydrosulfurizative reagent has been developed. Using DMAP as the catalyst, a variety of symmetric and asymmetric 1,3-diaryl thioureas were converted into the corresponding carbodiimides efficiently in a short time.

Synthesis, molecular and solid state structure of 5-(5-nitro furan-2-ylmethylen), 3-N-(2-methoxy phenyl), 2-N′-(2-methoxyphenyl) imino thiazolidin-4-one: X-ray powder diffraction and DFT studies

The 5-(5-nitro furan-2-ylmethylen), 3-N-(2-methoxy phenyl), 2-N′-(2-methoxyphenyl) imino thiazolidin-4-one compound has been synthesized and fully characterized by FT-IR, 1H and 13C NMR spectroscopy. The crystal structure of the titl

Synthesis of thioureas in ionic liquid medium

A highly efficient procedure for the synthesis of symmetrical thioureas by means of simple condensation of primary amines and carbon disulfide in 1-butyl-3-methylimidazolium chloride [BMIM][Cl] as a cheap and commercially available ionic liquid is presented. This procedure works for aromatic and aliphatic primary amines and give high to excellent yields of symmetrical thioureas without need for any catalyst or tedious work-up.

A simple and straightforward synthesis of phenyl isothiocyanates, symmetrical and unsymmetrical thioureas under ball milling

Promoted by KOH under ball milling, anilines were efficiently transformed into isothiocyanates (in presence of 5.0 equiv. CS2) or symmetrical thioureas (in presence of 1.0 equiv. CS2), without using any other harsh or toxic decomposition reagent. Some in situ generated isothiocyanates can directly "click" with other amines to afford unsymmetrical thioureas.

Synthesis and conformational features of sym N,N′,N″- triarylguanidines

A one pot reaction involving sym N,N′-diarylthiourea and the respective arylamine in the presence of aq. KOH in nitrobenzene at ≥105°C afforded sym N,N′,N″-triarylguanidine in fair to good yield and the products have been characterized. Sym N,N′,N″-tri(4-tolyl)guanidine possesses (7) anti-anti conformation, sym N,N′,N″-tri(2-tolyl) guanidine (8) and sym N,N′,N″-tris(2,4-xylyl)guanidine (11) each possess anti-anti αβα conformation whereas sym N,N′,N″-tris(2-anisyl)guanidine possesses (9) syn-anti αββ conformation as determined by single crystal X-ray diffraction data. The observed conformations appear to result from a subtle balance between steric factor associated with the aryl substituent and multiple electronic factors namely n-π conjugation/negative hyperconjugation and non-covalent interactions in the crystal lattice. Indian Academy of Sciences.

Practical synthesis of a vanilloid receptor-1 antagonist

(Chemical Equation Presented) Small molecule TRPV1 antagonists have been a recent focus in the search for pain treatment agents. We herein describe a practical and scalable synthesis of AMG 628 (1), a bis-substituted pyrimidine derivative that was identif

An environmentally benign method for the synthesis of symmetrical N,N′-disubstituted thioureas in a water medium

An environmentally benign method for the synthesis of symmetrical N,N′-disubstituted thioureas in a water medium using poly(ethylene glycol)-400 (PEG-400) as a catalyst and a microwave as a heating source is described. Diaryl- and dialkyl-thioureas efficiently are synthesized by the reactions of thiourea with a variety of amines. This protocol has advantages of (a) no use of hazardous reagents and volatile organic solvents, (b) a rapid reaction rate, (c) a high yield, and (d) a simple work-up procedure. Copyright Taylor & Francis Inc.