122643-81-6 Usage
Description
Ethanone, 1-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-, is a complex organic chemical compound characterized by the presence of a ketone group linked to a pyrazolo[1,5-a]pyridine ring, which is further substituted with a phenyl group. This unique molecular structure endows it with potential biological activities and makes it a promising candidate for pharmaceutical research and drug development. Its pharmacological properties, such as antioxidant, anti-inflammatory, or antimicrobial effects, are of particular interest, although further research is required to elucidate its full potential and mechanisms of action. Ethanone, 1-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-, thus stands as a noteworthy compound for exploration in medicinal chemistry.
Uses
Used in Pharmaceutical Research and Drug Development:
Ethanone, 1-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)is utilized as a compound of interest in pharmaceutical research and drug development due to its distinctive structural features and the potential for exhibiting a range of biological activities. Its exploration is driven by the possibility of it possessing pharmacological properties such as antioxidant, anti-inflammatory, or antimicrobial effects, which could be harnessed for the creation of novel therapeutic agents.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, Ethanone, 1-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)is employed as a subject of study for its potential to contribute to the discovery of new drugs. Ethanone, 1-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-'s unique structure and the possibility of it exhibiting beneficial pharmacological properties make it an attractive candidate for further investigation and development, with the aim of understanding its mechanisms of action and potential uses in treating various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 122643-81-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,2,6,4 and 3 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 122643-81:
(8*1)+(7*2)+(6*2)+(5*6)+(4*4)+(3*3)+(2*8)+(1*1)=106
106 % 10 = 6
So 122643-81-6 is a valid CAS Registry Number.
122643-81-6Relevant articles and documents
Pilot-scale synthesis of a novel non-xanthine adenosine A1 receptor antagonist. 1,3-dipolar cycloaddition of pyridine N-imine to an acetylene
Zanka, Atsuhiko,Hashimoto, Norio,Uematsu, Ryoichi,Okamoto, Takumi
, p. 320 - 324 (1998)
Adenosine A1 receptor antagonist, FK838, has been synthesized in 44% overall yield by a five-step sequence which is operationally straightforward and readily carried out on a large scale. Investigations into the 1,3-dipolar cycloaddition process that afforded a pyrazolo[1,5-a]pyridine derivative are also described. Process improvements and optimization of each step permitted elimination of column chromatography, resulting in a practical and cost-effective synthesis of FK838. These methods were successfully scaled up in a pharmaceutical pilot plant to give bulk drug used in clinical trials.
Double (amino-sulfur generation of formic acid ) - 1,3-propane diester compound and its synthetic method, pharmaceutical composition and use thereof
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Paragraph 0258; 0266-0269, (2016/10/08)
The invention relates to a bis(aminodithioformate)-1,3-propane diester compound, and synthesis method thereof, a pharmaceutical composition containing the compound and a use, and especially relates to the use in preparing drugs for treating or preventing cancers. The compound is represented as the formula (I), wherein A is selected from substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heterocyclic group, R1 and R2 are the same or different and are independently selected from hydrogen, alkyl, aryl alkyl or heteroaryl alkyl, or a substituted or unsubstituted heterocyclic ring formed together by the R1, the R2 and an N atom connected with the R1 and the R2.
Multi-gram scale synthesis of FR180204
Patnaik, Samarjit,Dietz, Harry C.,Zheng, Wei,Austin, Christopher,Marugan, Juan J.
experimental part, p. 8870 - 8873 (2010/03/01)
(Chemical Equation Presented) A concise synthesis of the ERK inhibitor FR180204 has been developed. The synthesis consists of six operationally simple steps and can be utilized to make multi-gram quantities of FR180204.
