39996-41-3

Usage

Chemical composition

1-aminopyridinium cation and mesitylenesulphonate anion.

Physical state

Crystalline material.

Category

Organic salt.

Usage

Chemical intermediate in organic synthesis.

Application

Building block for constructing functional materials.

Potential use

Organic light-emitting diodes and optoelectronic devices.

Field of interest

Materials science and organic chemistry.

Upstream product

• 110-86-1 pyridine 
• 36016-40-7 mesitylenesulfonylhydroxylamine 

Downstream Products

• 59942-95-9 1-Acetylpyrazolo<1,5-a>pyridine 
• 87290-01-5 pyridinium 1-[(phenyl)thiocarbonyl]aminide 
• 53687-87-9 3-benzoyl-2-methylthioimidazo<1,2-a>pyridine 
• 120590-35-4 3-benzoyl-8-methyl-2-methylthioimidazo<1,2-a>pyridine 
• 120590-34-3 3-benzoyl-6-methyl-2-methylthioimidazo<1,2-a>pyridine 
• 120590-36-5 3-benzoyl-6,8-dimethyl-2-methylthioimidazo<1,2-a>pyridine 
• 19364-00-2 1-Benzoylpyrazolo<1,5-a>pyridine 
• 106-49-0 p-toluidine 
• 108-44-1 1-amino-3-methylbenzene 
• 95-53-4 o-toluidine 
• 122643-81-6 2-phenyl-3-acetylpyrazolo[1,5-a]pyridine 
• 92-52-4 biphenyl 
• 62-53-3 aniline 
• 620-83-7 1-methyl-4-(phenylmethyl)benzene 

Relevant academic research and scientific papers

Heteroaryl imidazolone derivatives as jak inhibitors

New heteroaryl imidazolone derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Janus Kinases (JAK).

HETEROARYL IMIDAZOLONE DERIVATIVES AS JAK INHIBITORS

New heteroaryl imidazolone derivatives having the chemical structure of formula (I) disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Janus Kinases (JAK).

Structure-kinetics relations holding in the amination of six-membered nitrogen-containing heterocyclic compounds

Relative rates of the amination of 3-X- and 4-X-substituted pyridines (X = H, 3-Me, 4-Me, 3-F3C, 3-CN, 4-CN, 3-Cl, 3-Br, 4-MeO, 4-Me 2N), pyrazine, quinoline, isoquinoline, 2,2′- and 4,4′-bipyridines, and 1,10-phenanthroline with O-

Concise routes to pyrazolo[1,5-a]pyridin-3-yl pyridazin-3-ones

Cycloaddition of pyridine N-imine with 6-alkyl-4-oxohex-5-ynoates followed by condensation with hydrazine provides concise access to pharmacologically active 6-(pyrazolo[1,5-a]pyridin-3-yl)pyridazinones. For the first time alkynyl heterocycles are also shown to be effective dipolarophiles for pyridine N-imine, and analogous compounds can be accessed directly in modest yields through the reaction of 6-(alkyn-1-yl)pyridazin-3-one derivatives. The Royal Society of Chemistry 2008.

Synthesis of N-benzoylamino-1,2,3,6-tetrahydropyridine derivatives as potential anti-inflammatory agents

(Chemical Equation Presented) N-Benzoylamino-1,2,3,6-tetrahydropyridines 9a-q were synthesized from 4-substituted pyridines in four steps. Amination of pyridines was carried out to prepare intermediate N-aminopyridinium mesylates using mesytelenesulfonyl hydroxmate (MSH) as aminating agent. N-aminopyridinium mestylates reacted with appropriately substituted acyl chlorides to form N-ylides as stable crystalline solids. Partial reduction of N-ylides with mild reducing agent afforded N-benzoylamino-1,2,3,6-tetrahydropyridines in fair to good yields.