122751-47-7

Basic information

• Product Name: 2-Butenal, 4-(phenylmethoxy)-, (2Z)-
• CAS NO: 122751-47-7
• Molecular Formula: C11H12O2
• Molecular Weight: 176.215
• Mol File: 122751-47-7.mol
• Article Data: 22

Chemical Properties

• CAS DataBase Reference: 2-Butenal, 4-(phenylmethoxy)-, (2Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butenal, 4-(phenylmethoxy)-, (2Z)-(122751-47-7)
• EPA Substance Registry System: 2-Butenal, 4-(phenylmethoxy)-, (2Z)-(122751-47-7)

Safety Data

• Hazardous Substances Data: 122751-47-7(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 2568-24-3 2-phenyl-4,7-dihydro-1,3-dioxepine 
• 100-39-0 benzyl bromide 
• 81028-03-7 (Z)-4-benzyloxy-but-2-en-1-ol 
• 60656-87-3 benzyloxyacetoaldehyde 
• 2136-75-6 (triphenylphosphoranylidene)acetaldehyde 
• 100-44-7 benzyl chloride 
• 91142-50-6 4-benzyloxy-2-butyn-1-ol 
• 69152-88-1 4-(benzyloxy)-2-buten-1-ol 

Downstream Products

• 145969-02-4 (2Z)-4-((Z)-2-benzyloxyvinyl)-7-iodo-2-(N-methylanilino)hept-2-enenitrile 
• 145969-01-3 (2Z,5Z)-6-benzyloxy-4-(2-bromobenzyl)-2-(N-methylanilino)hexa-2,5-dienenitrile 
• 145969-00-2 (2Z,5E)-6-benzyloxy-4-(2-bromobenzyl)-2-(N-methylanilino)hexa-2,5-dienenitrile 
• 1350524-19-4 (3S,4S,5S)-5-((R)-2-(benzyloxy)-1-hydroxyethyl)-4-hydroxy-3-methyldihydrofuran-2(3H)-one 
• 1350524-25-2 (3S,4S,5R)-5-((S)-2-(benzyloxy)-1-hydroxyethyl)-4-hydroxy-3-methyldihydrofuran-2(3H)-one 

Relevant articles and documents

Asymmetric formation of bridged benzoxazocines through an organocatalytic multicomponent dienamine-mediated one-pot cascade

An organocatalytic one-pot cascade leading to the stereoselective formation of novel bridged benzoxazocines is presented. The developed methodology is based on the first example of a γ-selective-Mannich-initiated cascade reaction and allows for direct annulation of the bridged benzoxazocines by incorporation of various α,β-unsaturated aldehydes, electron-rich anilines, and electron-deficient salicylaldehydes. The synthetic applicability of the products is demonstrated by relevant transformations.

Copper-catalyzed method for preparing aldehyde or ketone compound by oxidizing alcohol with oxygen as oxidizing agent and application

The invention discloses a copper-catalyzed method for preparing an aldehyde or ketone compound by oxidizing alcohol with oxygen as an oxidizing agent. Reaction is performed in an organic solvent for 4-48 hours at room temperature by using copper salt and nitroxide free radicals as catalysts and oxygen or air as an oxidizing agent to efficiently oxidize an alcohol compound into the corresponding aldehyde or ketone compound. The method is simple to operate, free of chlorides corrosive to equipment, available in raw materials and reagents, mild in reaction conditions, wide in substrate universality, good in functional group compatibility, convenient in separation and purification, environmentally friendly in the whole process and free of pollution, and is a method suitable for industrial production.

A TEMPO-free copper-catalyzed aerobic oxidation of alcohols

The copper-catalyzed aerobic oxidation of primary and secondary alcohols without an external N-oxide co-oxidant is described. The catalyst system is composed of a Cu/diamine complex inspired by the enzyme tyrosinase, along with dimethylaminopyridine (DMAP) or N-methylimidazole (NMI). The Cu catalyst system works without 2,2,6,6-tetramethyl-l-piperidinoxyl (TEMPO) at ambient pressure and temperature, and displays activity for un-activated secondary alcohols, which remain a challenging substrate for catalytic aerobic systems. Our work underscores the importance of finding alternative mechanistic pathways for alcohol oxidation, which complement Cu/TEMPO systems, and demonstrate, in this case, a preference for the oxidation of activated secondary over primary alcohols.