122804-35-7

Upstream product

• 67-56-1 methanol 
• 144666-93-3 (2S,3R)-3-Benzyloxymethyl-2-methyl-2-(4-methyl-pent-3-enyl)-oxirane 
• 103-50-4 dibenzyl ether 
• 50727-94-1 [3-methyl-3-(4-methylpent-3-enyl)oxiran-2-yl]methanol 
• 100-39-0 benzyl bromide 
• 62777-72-4 (2R,3S)-2,3-epoxynerol 

Downstream Products

• 122804-38-0 (2R,3R)-1-benzyloxy-2-t-butyldimethylsiloxy-3-methoxy-3-methyl-6-heptene 
• 122804-37-9 (2R,3R)-1-benzyloxy-3-methyl-3-methyl-6-heptene-2-ol 
• 122804-36-8 (4R,5R)-6-Benzyloxy-5-hydroxy-4-methoxy-4-methyl-hexanal 

Relevant academic research and scientific papers

Towards a Large Scale Preparation of Mexiprostil

The enantioselective synthesis of mexiprostil (16R-16-methoxy-16-methyl PGE1 methyl ester) is described.The assembly of the prostaglandin framework has been accomplished by the three component coupling process, via consecutive linking of the ω

Novel process and intermediates

This invention relates to the novel processes for the preparation of a 16-methoxy-16-methyl prostaglandin E1 derivative and to the novel intermediates useful therefor.

Improvement process for debrominative rearrangements

This invention relates to an improvement in the standard procedures involving a debrominative rearrangement reaction of a terminal dibromoolefin with activated magnesium in tetrahydrofuran.