1228255-36-4Relevant academic research and scientific papers
Concise synthesis of polymethoxyflavone sudachitin and its derivatives, and biological evaluations
Sagara, Hiroto,Kanakogi, Masaki,Tara, Yuki,Ouchi, Hitoshi,Kimura, Junko,Kaneko, Yukiko,Inai, Makoto,Asakawa, Tomohiro,Ishikawa, Tomohisa,Kan, Toshiyuki
, p. 1816 - 1818 (2018)
We accomplished a divergent synthesis of sudachitin (2), a polymethoxyflavone isolated from citrus fruits, and six derivatives from acetophenone 9, which was an intermediate in our previous synthesis of nobiletin (1). Compound 2 enhanced glucose-induced i
A simple route toward new clomiphene metabolites
Vitoriano, Bruno C.,Carvalho, Luísa C. R.,Estev?o, Mónica S.,Sekera, Michael H.,Marques, M. Manuel B.
supporting information; experimental part, p. 753 - 756 (2010/06/13)
A new clomiphene metabolite, extremely useful for doping analysis, was synthesized in 19% overall yield. The approach involved a Grignard reaction via a N-acylbenzotriazole intermediate to afford a key aromatic ketone and a HWE reaction. Both stereo-isomers were separated and identified. Georg Thieme Verlag Stuttgart ? New York.
