1228934-55-1

Basic information

• Product Name: 6-{2-[(2R)-2-(3,5-dimethylbenzyl)piperidin-1-yl]-2-oxoethyl}-4-(1H-indazol-3-ylmethyl)-1-phenyl-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-5(6H)-one
• Synonyms: 6-{2-[(2R)-2-(3,5-dimethylbenzyl)piperidin-1-yl]-2-oxoethyl}-4-(1H-indazol-3-ylmethyl)-1-phenyl-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-5(6H)-one
• CAS NO: 1228934-55-1
• Molecular Weight: 649.795
• Mol File: 1228934-55-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-{2-[(2R)-2-(3,5-dimethylbenzyl)piperidin-1-yl]-2-oxoethyl}-4-(1H-indazol-3-ylmethyl)-1-phenyl-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-5(6H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-{2-[(2R)-2-(3,5-dimethylbenzyl)piperidin-1-yl]-2-oxoethyl}-4-(1H-indazol-3-ylmethyl)-1-phenyl-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-5(6H)-one(1228934-55-1)
• EPA Substance Registry System: 6-{2-[(2R)-2-(3,5-dimethylbenzyl)piperidin-1-yl]-2-oxoethyl}-4-(1H-indazol-3-ylmethyl)-1-phenyl-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-5(6H)-one(1228934-55-1)

Safety Data

• Hazardous Substances Data: 1228934-55-1(Hazardous Substances Data)

Upstream product

• 174180-42-8 2-methyl-2-propanyl 3-(bromomethyl)-1H-indazole-1-carboxylate 
• 64132-13-4 3-(hydroxymethyl)-1H-indazole 
• 1228935-05-4 tert-butyl 3-{[6-(2-tert-butoxy-2-oxoethyl)-5-oxo-1-phenyl-5,6-dihydro-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-4-yl]methyl}-1H-indazole-1-carboxylate 
• 1228935-17-8 (2R)-1-(chloroacetyl)-2-(3,5-dimethylbenzyl)piperidine 
• 1228935-15-6 (R)-2-(3,5-dimethylbenzyl)piperidine 
• 1228935-13-4 2-(3,5-dimethylbenzyl)piperidine 
• 556-96-7 5-bromo-1,3-xylene 
• 92906-86-0 (3,5-dimethylphenyl)pyridin-2-ylmethanol 
• 1121-60-4 pyridine-2-carbaldehyde 
• 1228935-19-0 tert-butyl 3-{[(methylsulfonyl)oxy]methyl}-1H-indazole-1-carboxylate 
• 1228935-18-9 6-{2-[(2R)-2-(3,5-dimethylbenzyl)piperidin-1-yl]-2-oxoethyl}-1-phenyl-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-5(6H)-one 
• 1228935-06-5 [4-(1H-indazol-3-yl-methyl)-5-oxo-1-phenyl-4,5-dihydro-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-6-yl]acetic acid 

Downstream Products

• 1228934-52-8 (4S)-6-{2-[(2R)-2-(3,5-dimethylbenzyl)piperidin-1-yl]-2-oxoethyl}-4-(1H-indazol-3-ylmethyl)-1-phenyl-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-5(6H)-one 

Relevant articles and documents

1,2,4 TRIAZOLO [4, 3 -A] [1,5] BENZODIAZEPIN-5 (6H) -ONES AS AGONISTS OF THE CHOLECYSTOKININ-1 RECEPTOR (CCK-IR)

This invention relates to CCK-1 R agonists of Formula (I) wherein R1-R5 and X are as defined in the specificiation, as well as pharmaceutical compositions containing the compounds and methods of use of the compounds and compositions. The compounds are useful in treating obesity, type 2 diabetes and associated diseases.