122920-65-4Relevant academic research and scientific papers
Bis(mandelato)borate: An effective, inexpensive spiroborate anion for chiral resolution
Wong, Lawrence W-Y.,Kan, Jack W-H.,Nguyen, Thanh-Ha,Sung, Herman H-Y.,Li, Dang,Au-Yeung, Alex S-F.,Sharma, Rajpal,Lin, Zhenyang,Williams, Ian D.
, p. 15760 - 15763 (2015)
Bis(mandelato)borate [B(Man)2]- (R- or S-) anions are simply prepared and appear widely effective for resolution of racemic cations. Three examples demonstrate their scope; the alkaloid tetrahydropalmatine (THP), 1,2-diaminopropane (1,2-dap) and the metal-organic complex [Co(phen)3]3+ are readily resolved, either by a facile one-pot procedure, or via counter-ion metathesis.
SYNTHESIS OF CHIRAL 1,2-DIAMINES
Bruni, Elena,Cardillo, Giuliana,Orena, Mario,Sandri, Sergio,Tomasini, Claudia
, p. 1679 - 1682 (2007/10/02)
(1'S,5R,S)-(1'-phenyleth-1'-yl)-5-iodomethyl-imidazolines 4a, b have been synthesised and easily resolved by silica gel chromatography.The correlation between the configuration and the 1H-NMR chemical shifts allows to assign the configuration at the C-5 of these intermediates.Each pure diastereomer has been converted to R(-)- and to S(+)-1,2-propyldiamine, respectively.
