123266-63-7

Basic information

• Product Name: 2,3-DIHYDRO-1-BENZOFURAN-7-CARBONYL CHLORIDE
• Synonyms: 2,3-DIHYDRO-1-BENZOFURAN-7-CARBONYL CHLORIDE;BUTTPARK 97\04-62;2,3-Dihydrobenzo[b]furan-7-carbonyl chloride;7-Benzofurancarbonyl chloride, 2,3-dihydro- (9CI);2,3-Dihydro-1-benzofuran-7-carbonyl chloride, 7-(Chlorocarbonyl)-2,3-dihydrobenzo[b]furan;2,3-dihydrobenzofuran-7-carbonyl chloride;7-BENZOFURANCARBONYL CHLORIDE, 2,3-DIHYDRO
• CAS NO: 123266-63-7
• Molecular Formula: C₉H₇ClO₂
• Molecular Weight: 182.6
• Product Categories: ACIDHALIDE
• Mol File: 123266-63-7.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 299.8 °C at 760 mmHg
• Flash Point: 111.6 °C
• Appearance: /
• Density: 1.342 g/cm³
• Vapor Pressure: 0.00116mmHg at 25°C
• Refractive Index: 1.586
• CAS DataBase Reference: 2,3-DIHYDRO-1-BENZOFURAN-7-CARBONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DIHYDRO-1-BENZOFURAN-7-CARBONYL CHLORIDE(123266-63-7)
• EPA Substance Registry System: 2,3-DIHYDRO-1-BENZOFURAN-7-CARBONYL CHLORIDE(123266-63-7)

Safety Data

• Hazard Codes: C
• Hazardous Substances Data: 123266-63-7(Hazardous Substances Data)

Usage

General Description

2,3-Dihydro-1-benzofuran-7-carbonyl chloride, also known as 2,3-Dihydro-7-formyl-1-benzofuran Chloride, is a chemical compound that is commonly used in organic synthesis and medicinal chemistry. It is a benzofuran derivative with a carbonyl chloride (COCl) functional group attached to the 7th carbon of the benzofuran ring. 2,3-DIHYDRO-1-BENZOFURAN-7-CARBONYL CHLORIDE is a versatile building block in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. It is also used as a reagent for the preparation of heterocyclic compounds and in the development of new drug molecules. The carbonyl chloride functionality in this compound makes it reactive and useful for forming various chemical bonds in organic synthesis.

InChI:InChI=1/C9H7ClO2/c10-9(11)7-3-1-2-6-4-5-12-8(6)7/h1-3H,4-5H2

Upstream product

• 35700-40-4 2,3-dihydrobenzofuran-7-carboxylic acid 
• 79-37-8 oxalyl dichloride 
• 119-36-8 methyl salicylate 
• 69-72-7 salicylic acid 
• 75855-24-2 2-Hydroxy-3-vinyl-benzoic acid methyl ester 
• 133844-95-8 2,3-dihydro-benzofuran-7-carboxylic acid methyl ester 
• 13661-90-0 2-vinyloxy-benzoic acid methyl ester 
• 496-16-2 2.3-dihydrobenzofuran 

Downstream Products

• 149530-56-3 2,3-Dihydro-N-<4-(1,1-dimethylethyl)phenylmethyl>-N-methyl-7-benzofurancarboxamid 
• 170730-06-0 1-(2,3-dihydrobenzofuran-7-yl)ethanone 
• 99517-45-0 methyl benzofuran-7-carboxylate 
• 90484-22-3 7-benzofuranylcarboxylic acid 
• 133844-95-8 2,3-dihydro-benzofuran-7-carboxylic acid methyl ester 
• 883120-58-9 N-(2-(1H-pyrazol-1-yl)phenyl)-2,3-dihydrobenzofuran-7-carboxamide 

Relevant articles and documents

Vascular endothelial growth factor receptor inhibitor and preparation method and application thereof

The invention provides a vascular endothelial growth factor receptor inhibitor and a preparation method and application thereof, and relates to a quinoline or quinazoline derivative with a structure as shown in a formula (I), a pharmaceutical composition containing a compound as shown in the formula (I) and application of the compound in preparation of drugs for preventing or treating angiogenesis-related diseases, in particular to prevention or treatment of tumors related to protein tyrosine kinase. Each substituent in the formula (I) is the same as the definition in the specification.

NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF

The present invention relates to compounds of formula (I), or pharmaceutical salts, prodrugs, salts of prodrugs, or combinations thereof, formula (I). wherein R1, R2, R3, R4, and L1 are defined in the specfication, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions. The present invention also relates to compounds of formula (II), or pharmaceutical salts, prodrugs, salts of prodrugs, or combinations thereof, formula (II). wherein R1a, R2a, Rx, and n are as defined in the specification, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.

NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF

The present invention relates to compounds of formula (I), or pharmaceutical salts, prodrugs, salts of prodrugs, or combinations thereof, wherein R1, R2, R3, and L1 are defined in the specfication, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions. The present invention also relates to compounds of formula (II), or pharmaceutical salts, prodrugs, salts of prodrugs, or combinations thereof, wherein R1a, R2a and (Rx)n are as defined in the specification, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.