1235384-23-2Relevant academic research and scientific papers
Flash chemistry using trichlorovinyllithium: Switching the reaction pathways by high-resolution reaction time control
Nagaki, Aiichiro,Takahashi, Yusuke,Henseler, Andrea,Matsuo, Chika,Yoshida, Jun-Ichi
, p. 214 - 216 (2015/03/05)
High-resolution reaction time control in flow microreactors enables the reaction-pathway switching of trichlorovinyllithium generated by the H/Li exchange of trichloroethene. The method was successfully app lied to the synthesis of 1,1,2-trichloroalkenes,
Lithiation of 1,2-dichloroethene in flow microreactors: Versatile synthesis of alkenes and alkynes by precise residence-time control
Nagaki, Aiichiro,Matsuo, Chika,Kim, Songhee,Saito, Kodai,Miyazaki, Atsuo,Yoshida, Jun-Ichi
supporting information; experimental part, p. 3245 - 3248 (2012/05/31)
It′s all about the timing: Precise control of the residence time (tRx; see picture) of reactive intermediates in flow microreactors enables the reaction pathway of lithiated 1,2-dichloroethene to be switched to produce either alkenes or alkynes. This method also allows versatile syntheses of asymmetric disubstituted dichloroalkenes and alkynes. Copyright
