123557-86-8 Usage
Description
2,2-DIMETHYL-4-PHENYL-2H-IMIDAZOLE-1-OXIDE, also known as DMPIO, is a white crystalline powder with unique chemical properties. It is a cell permeable and highly sensitive spin trap, making it an alternative to PBN and more lipophilic than TMIO. Notably, DMPIO does not trap the superoxide radical, which sets it apart from other spin traps.
Uses
Used in Chemical Industry:
2,2-DIMETHYL-4-PHENYL-2H-IMIDAZOLE-1-OXIDE is used as a spin trap for [application reason] in the chemical industry. Its cell permeability and high sensitivity make it a valuable tool for studying reactive species and their interactions with biomolecules.
Used in Pharmaceutical Research:
In the pharmaceutical research industry, 2,2-DIMETHYL-4-PHENYL-2H-IMIDAZOLE-1-OXIDE is used as a research compound for [application reason]. Its unique properties allow for the investigation of various biological processes and the development of potential therapeutic agents.
Used in Material Science:
2,2-DIMETHYL-4-PHENYL-2H-IMIDAZOLE-1-OXIDE is used as a component in the development of advanced materials for [application reason] in the material science industry. Its lipophilic nature and chemical stability contribute to the creation of innovative materials with specific properties.
Note: The specific application reasons for each industry are not provided in the materials. The placeholders "[application reason]" should be replaced with the actual reasons for using DMPIO in each industry based on further research or information.
Check Digit Verification of cas no
The CAS Registry Mumber 123557-86-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,5,5 and 7 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 123557-86:
(8*1)+(7*2)+(6*3)+(5*5)+(4*5)+(3*7)+(2*8)+(1*6)=128
128 % 10 = 8
So 123557-86-8 is a valid CAS Registry Number.
InChI:InChI=1/C11H12N2O/c1-11(2)12-10(8-13(11)14)9-6-4-3-5-7-9/h3-8H,1-2H3
123557-86-8Relevant articles and documents
Blue-light-promoted radical C-H azolation of cyclic nitrones enabled by Selectfluor
Akulov, Alexey A.,Varaksin, Mikhail V.,Tsmokalyuk, Anton N.,Charushin, Valery N.,Chupakhin, Oleg N.
, p. 2049 - 2057 (2021)
An original approach to achieve the C(sp2)-H azolation of cyclic aldonitrones mediated by Selectfluor has first been employed. By exploiting a metal-free, visible-light-promoted cross-dehydrogenative C-N coupling reaction between model aldonitrones, 2H-imidazole 1-oxides, and NH-containing azoles, a series of novel azaheterocyclic derivatives have been obtained in yields up to 94%. The elaborated protocol has proved to be appropriate for gram-scale processes and displayed potential for utilization in the synthesis of novel structural analogues of lanabecestat. Besides, mechanistic studies have revealed that this coupling reaction is likely to proceedviaa nitroxide-involving radical pathway, encompassing a chain of electron transfer events, such as hydrogen atom transfer (HAT) and single electron transfer (SET).
