1235575-91-3

Upstream product

• 1199793-11-7 2-amino-1-(4-chloro-3-fluorophenyl)-2-(6-chloropyridin-3-yl)propan-1-one 
• 1199793-06-0 ethyl 2-amino-2-(6-chloropyridin-3-yl)propanoate 
• 1033719-20-8 (4S,5R)-5-(4-chloro-3-fluorophenyl)-4-(6-chloropyridin-3-yl)-4-methylimidazolidine-2-thione 
• 1199793-12-8 2-chloro-5-[4-(4-chloro-3-fluorophenyl)-3-methyl-1,1-dioxido-2,3-dihydro-1,2,5-thiadiazol-3-yl]pyridine 
• 1199793-10-6 tert-butyl [2-(4-chloro-3-fluorophenyl)-1-(6-chloropyridin-3-yl)-1-methyl-2-oxoethyl]carbamate 
• 1199793-09-3 tert-butyl [2-(4-chloro-3-fluorophenyl)-1-(6-chloropyridin-3-yl)-2-hydroxy-1-methylethyl]carbamate 
• 1199793-08-2 tert-butyl [1-(6-chloropyridin-3-yl)-1-methyl-2-oxoethyl] carbamate 
• 1199793-07-1 ethyl 2-[(tert-butoxycarbonyl)amino]-2-(6-chloropyridin-3-yl)propanoate 
• 1033719-23-1 (5R,6S)-5-(4-Chloro-3-fluorophenyl)-6-(6-chloropyridin-3-yl)-3-isopropyl-6-methyl-5,6-dihydroimidazo[2,1-b][1,3]thiazole-2-carboxylic acid 
• 1033719-22-0 Ethyl (5R,6S)-5-(4-Chloro-3-fluorophenyl)-6-(6-chloropyridin-3-yl)-3-isopropyl-6-methyl-5,6-dihydroimidazo[2,1-b][1,3]thiazole-2-carboxylate 
• 1033719-19-5 (1R,2S)-1-(4-Chloro-3-fluorophenyl)-2-(6-chloropyridin-3-yl)propane-1,2-diamine 
• 55676-22-7 3-acetyl-6-chloropyridine 
• 1235576-41-6 tert-butyl (2S,4R)-4-fluoro-2-{[4-(trifluoroacetyl)-4,7-diazaspiro[2.5]oct-7-yl]carbonyl}pyrrolidine-1-carboxylate 
• 1235576-26-7 7-[(4R)-1-{[(5R,6S)-5-(4-chloro-3-fluorophenyl)-6-(6-chloropyridin-3-yl)-3-isopropyl-6-methyl-5,6-dihydroimidazo[2,1-b][1,3]thiazol-2-yl]carbonyl}-4-fluoro-L-prolyl]-4-(trifluoroacetyl)-4,7-diazaspiro[2.5]octane 

Downstream Products

• 1235576-07-4 7-[(4R)-1-{[(5R,6S)-5-(4-chloro-3-fluorophenyl)-6-(6-chloropyridin-3-yl)-3-isopropyl-6-methyl-5,6-dihydroimidazo[2,1-b][1,3]thiazol-2-yl]carbonyl}-4-fluoro-L-prolyl]-4-methyl-4,7-diazaspiro[2.5]octane 

Relevant academic research and scientific papers

IMIDAZOTHIAZOLE DERIVATIVE HAVING PROLINE RING STRUCTURE

[Problem to be Solved] There is provided a novel compound that inhibits interaction between murine double minute 2 (Mdm2) protein and p53 protein and exhibits anti-tumor activity. [Solution] The present invention provides an imidazothiazole derivative rep