1236196-77-2 Usage
Uses
Used in Chemical Biology:
4-(4-(prop-2-ynyloxy)benzoyl)benzoic acid is used as a chemical probe for protein photolabeling and the synthesis of Thiodigalactoside-Based chemical probes to label galectin-3. Its light-activated benzophenone allows for UV light-induced covalent modification of biological targets, enabling researchers to study protein-ligand interactions and develop new therapeutic agents.
Used in Drug Discovery:
4-(4-(prop-2-ynyloxy)benzoyl)benzoic acid is used as a trifunctional building block in drug discovery, providing a versatile synthetic handle for the development of new chemical probes. By appending this building block to a ligand or pharmacophore through its acid linker, researchers can create light-activated probes that enable the study of biological targets and the optimization of probe design for chemical biology experiments.
Used in Chemical Synthesis:
4-(4-(prop-2-ynyloxy)benzoyl)benzoic acid is used as a synthetic building block in chemical synthesis, offering a light-activated benzophenone, alkyne tag, and carboxylic acid handle for the creation of new chemical probes and ligands. Its multifunctional nature allows for the development of innovative chemical structures with potential applications in various fields, including drug discovery, chemical biology, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 1236196-77-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,6,1,9 and 6 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1236196-77:
(9*1)+(8*2)+(7*3)+(6*6)+(5*1)+(4*9)+(3*6)+(2*7)+(1*7)=162
162 % 10 = 2
So 1236196-77-2 is a valid CAS Registry Number.
1236196-77-2Relevant academic research and scientific papers
Synthesis of trifunctional phosphatidylserine probes for identification of lipid-binding proteins
Bandyopadhyay, Saibal,Bong, Dennis
, p. 751 - 758 (2011/03/22)
Phosphatidylserine (PS) lipids play a number of roles in cell biology, one of which is to mark apoptotic cells for clearance by macrophages. PS recognition triggers macrophage recognition and clearance, which occurs concomitantly with active suppression o
