123743-15-7

Basic information

• Product Name: 6-chloro-2-(4-methoxyphenyl)chroman-4-one
• CAS NO: 123743-15-7
• Molecular Weight: 288.73
• Mol File: 123743-15-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 6-chloro-2-(4-methoxyphenyl)chroman-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-2-(4-methoxyphenyl)chroman-4-one(123743-15-7)
• EPA Substance Registry System: 6-chloro-2-(4-methoxyphenyl)chroman-4-one(123743-15-7)

Safety Data

• Hazardous Substances Data: 123743-15-7(Hazardous Substances Data)

Upstream product

• 1450-74-4 5-chloro-2-hydroxyacetophenone 
• 123-11-5 4-methoxy-benzaldehyde 
• 1226-09-1 (E)-1-(5-chloro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-prop-2-en-1-one 
• 116194-65-1 6-Chloro-2-(4-methoxy-phenyl)-chroman-4-ol 
• 123743-11-3 6-Chloro-2-(4-methoxy-phenyl)-chroman-4-one oxime 
• 126267-42-3 2'-hydroxy-5'-chloro-4-methoxychalcone 

Downstream Products

• 1393598-17-8 9-chloro-5-(4-methoxyphenyl)-2-piperidino-5H-chromeno[3,4-c]pyridine-1-carbonitrile 
• 130252-74-3 6-chloro-3-(4-methoxyphenyl)-4H-chromene-4-one 
• 63046-14-0 6-chloro-2-(4-methoxy-phenyl)-chromen-4-one 

Relevant articles and documents

Synthesis of 5-aryl-2-piperidino-5H-chromeno[3,4-c]pyridine-1-carbonitriles

4-Chloro-2-aryl-2H-3-chromenecarbaldehydes 3a-g on reaction with malononitrile in ethanol in the presence of piperidine gave 5-aryl-2-piperidino- 5H-chromeno[3,4-c]pyridine-1-carbonitriles 4a-g in good yields. ARKAT-USA, Inc.

Highly diastereoselective Michael reaction under solvent-free conditions using microwaves: Conjugate addition of flavanone to its chalcone precursor

Microwave-assisted reaction of 2′-hydroxychalcones in the presence of DBU resulted in the formation of hitherto unknown dimers by conjugate addition of the intermediate cyclic ketone to the starting enone.

Simple technics for isomerization of 2'-hydroxychalcones to flavanones: Use of silica gel, ethylenediamine and hydroxylamine hydrochloride

2'-Hydroxychalcones (1) are isomerized to flavanones (2) by treatment with silica gel, ethylenediamine or hydroxylamine hydrochloride at low temperatures.