123761-13-7

Basic information

• Product Name: methyl 3-amino-2-benzylpropanoate
• Synonyms: methyl 3-amino-2-benzylpropanoate
• CAS NO: 123761-13-7
• Molecular Weight: 193.246
• Mol File: 123761-13-7.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: methyl 3-amino-2-benzylpropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-amino-2-benzylpropanoate(123761-13-7)
• EPA Substance Registry System: methyl 3-amino-2-benzylpropanoate(123761-13-7)

Safety Data

• Hazardous Substances Data: 123761-13-7(Hazardous Substances Data)

Upstream product

• 104-55-2 3-phenyl-propenal 
• 14533-85-8 methyl (2Z)-2-cyano-3-phenyl acrylate 
• 14533-86-9 methyl (E)-2-cyano-3-phenylprop-2-enoate 
• 100-52-7 benzaldehyde 
• 100-51-6 benzyl alcohol 
• 3695-84-9 methyl benzylidenecyanoacetate 
• 124916-61-6 (S)-2-bromo-3-penylpropanoic acid methyl ester 
• 35016-63-8 (S)-2-bromo-3-phenylpropionic acid 
• 63-91-2 L-phenylalanine 
• 887143-10-4 methyl 2-[(dibenzylamino)methyl]-3-phenylpropionate 
• 124957-36-4 Methyl 3-acetoxy-2-methylene-3-phenylpropanoate 
• 1404370-96-2 methyl 2-benzyl-3-[(R)-1-phenylethylamino]propanoate 
• 18020-59-2 methyl 3-hydroxy-2-methylidene-3-phenylpropionate 
• 1404371-20-5 methyl (Z)-3-phenyl-2-{[(R)-1-phenylethylamino]methyl}acrylate 

Downstream Products

• 131683-27-7 (S)-(–)-β²-homophenylalanine 
• 1005187-98-3 2-[(2-methoxycarbonyl-acetylamino)-methyl]-3-phenyl-propionic acid methyl ester 
• 1448639-64-2 (S)-methyl 2-benzyl-3-((S)-2-benzyl-3-((tert-butoxycarbonyl)amino)propanamido) propanoate 
• 1448639-61-9 (S)-methyl 2-benzyl-3-((S)-3-(tert-butoxycarbonylamino)-4-phenylbutanamido) propanoate 
• 95598-13-3 (+/-)-α-benzyl-β-aminopropionic acid 
• 123542-78-9 (S)-2-<<(S)-2-(6-Methoxy-2-naphthyl)propionylamino>methyl>-3-phenylpropionsaeure-methylester 
• 123761-08-0 2-[(4-Chloro-benzylamino)-methyl]-3-phenyl-propionic acid 
• 26250-90-8 (3R)-benzyl-3-(tert-butoxycarbonyl)amino-propanoic acid 

Relevant articles and documents

EIF4E INHIBITORS AND USES THEREOF

The present invention provides compounds inhibiting elF4E activity and compositions and methods of using thereof.

Chemical assembly systems: Layered control for divergent, continuous, multistep syntheses of active pharmaceutical ingredients

While continuous chemical processes have attracted both academic and industrial interest, virtually all active pharmaceutical ingredients (APIs) are still produced by using multiple distinct batch processes. To date, methods for the divergent multistep continuous production of customizable small molecules are not available. A chemical assembly system was developed, in which flow-reaction modules are linked together in an interchangeable fashion to give access to a wide breadth of chemical space. Control at three different levels - choice of starting material, reagent, or order of reaction modules - enables the synthesis of five APIs that represent three different structural classes (γ-amino acids, γ-lactams, β-amino acids), including the blockbuster drugs Lyrica and Gabapentin, in good overall yields (49-75%).

Design and structure-activity relationships of potent and selective inhibitors of undecaprenyl pyrophosphate synthase (UPPS): Tetramic, tetronic acids and dihydropyridin-2-ones

Based on a pharmacophore hypothesis substituted tetramic and tetronic acid 3-carboxamides as well as dihydropyridin-2-one-3-carboxamides were investigated as inhibitors of undecaprenyl pyrophosphate synthase (UPPS) for use as novel antimicrobial agents. S