1239892-68-2

Upstream product

• 87604-48-6 (R)-4-((R)-Benzyloxy-phenyl-methyl)-2,2-dimethyl-[1,3]dioxolane 
• 16354-89-5 (R)-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl](phenyl)methanol 
• 100-44-7 benzyl chloride 

Downstream Products

• 13136-54-4 (R)-Benzyloxy-phenyl-acetic acid 
• 87604-59-9 2-benzyloxy-2-phenyl ethanol 
• 87604-57-7 (R)-2-(benzyloxy)-2-phenylacetaldehyde 

Relevant academic research and scientific papers

Co(iii)(salen)-catalyzed HKR of two stereocentered alkoxy- and azido epoxides: A concise enantioselective synthesis of (S,S)-reboxetine and (+)-epi-cytoxazone

The HKR of racemic syn- or anti- alkoxy- and azido epoxides catalyzed by Co(salen) complex affords a practical access to a series of enantioenriched syn- or anti- alkoxy- and azido epoxides and the corresponding 1,2-diols. This strategy has been successfully employed in the concise, enantioselective synthesis of bioactive molecules such as (S,S)-reboxetine and (+)-epi-cytoxazone.

ON THE STERIC COURSE OF THE ADDITION OF SOME ORGANOMETALLIC REAGENTS TO (R)-2,3-ISOPROPYLIDENE GLYCERALDEHYDE. SYNTHESIS OF OPTICALLY ACTIVE α-BENZYLOXY ALDEHYDES, ALCOHOLS, CARBOXYLIC ACIDS AND 1,2-DIOLS.

Organo-titanium and organo-zinc reagents were added stereoselectively to (R)-2,3-isopropylidene glyceraldehyde (1) to give the alcohols 2/3, which were converted into the optically active derivatives 4-11.