87604-57-7

Upstream product

• 133420-97-0 methyl (R)-2-benzyloxy-2-phenylacetate 
• 100-52-7 benzaldehyde 
• 611-71-2 (R)-Mandelic Acid 
• 20698-91-3 (R)-methyl mandelate 
• 100-44-7 benzyl chloride 
• 87604-48-6 (R)-4-((R)-Benzyloxy-phenyl-methyl)-2,2-dimethyl-[1,3]dioxolane 
• 16354-89-5 (R)-[(R)-2,2-dimethyl-1,3-dioxolan-4-yl](phenyl)methanol 
• 156480-55-6 (2S,4S,5R)-2-(1R)-(1-hydroxy-1-phenyl)methyl-4-methyl-5-phenyl-3-tert-butoxycarbonyloxazolidine 
• 156365-81-0 (2S,4S,5R)-4-methyl-2-(1-oxo-1-phenyl)methyl-5-phenyl-3-tert-butoxycarbonyloxazolidine 
• 156480-57-8 (2S,4S,5R)-2-((R)-Benzyloxy-phenyl-methyl)-4-methyl-5-phenyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 100-39-0 benzyl bromide 
• 186414-20-0 Phenyl-[(2R,4aR,6S,7R,8S,8aR)-6,7,8-trimethoxy-3-(toluene-4-sulfonyl)-octahydro-pyrano[2,3-e][1,3]oxazin-2-yl]-methanone 
• 186414-25-5 (R)-Phenyl-[(2R,4aR,6S,7R,8S,8aR)-6,7,8-trimethoxy-3-(toluene-4-sulfonyl)-octahydro-pyrano[2,3-e][1,3]oxazin-2-yl]-methanol 
• 216760-16-6 (R)-2-((R)-Benzyloxy-phenyl-methyl)-4,4-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 

Downstream Products

• 133420-95-8 [(R)-2-Benzyloxy-2-phenyl-eth-(Z)-ylidene]-((S)-2-methoxymethyl-pyrrolidin-1-yl)-amine 
• 87604-59-9 2-benzyloxy-2-phenyl ethanol 
• 13136-54-4 (R)-Benzyloxy-phenyl-acetic acid 

Relevant academic research and scientific papers

Formation and reaction of 2-metalated N-Boc-4,4-dimethyl-1,3- oxazolidines in the presence of (-)-sparteine: New chiral formyl anion equivalents

Lithiation of N-Boc-4,4-dimethyl-1,3-oxazolidine with s-BuLi and the following reaction with benzaldehyde was carried out in the presence of (-)- sparteine. The reaction was not diastereoselective (syn:anti=46:54), but each isomer of the adducts was obtai

Diastereoselective reduction of chiral N-tosyl 2-benzoyl-1,3-oxazines derived from D-glucose

Stereochemistry of reduction of the diastereomerically pure N-tosyl 2-benzoyl-1,3-oxazines prepared from D-glucose was investigated with various reducing agents. It was found that the stereachemical outcome is consistent with the Cram's chelation model where the ring oxygen atom is involved in chelation, not the tosyl oxygen as in the 5-membered oxazolidines.

Chiral 2-lithio-13-dioxolanes and - 2-lithiooxazolidines: New formyl anion equivalents

The preparation of enantiomerically pure 2-lithio-1,3-dioxolanes and 2-lithiooxazolidines and their use as formyl anion equivalents in addition reactions to aldehydes are described.

Benzo-fused lactams that promote the release of growth hormone

There are disclosed certain novel compounds identified as benzo-fused lactams which promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production of edible meat products more efficient, and in humans, to increase the stature of those afflicted with a lack of a normal secretion of natural growth hormone. Growth promoting compositions containing such benzo-fused lactams as the active ingredient thereof are also disclosed.

Synthesis of O-Protected (R)-2-Hydroxy Aldehyde and Their Hydrocyanation

The synthesis of O-silyl- and O-benzyl-protected (R)-2-hydroxy aldehydes (R)-6 from (R)-2-hydroxy carboxylic acids (R)-1 is described.While attempts for their diastereoselective hydrocyanation with hydrocyanic acid and (R)-oxynitrilase as catalyst have not been successful, the cyano silylation with trimethylsilyl cyanide occurred diastereoselectively with a ratio of 81:19 preferring the threo form without racemization at C-2 of the 2-hydroxy aldehyde. Key Words : (R)-2-Hydroxy aldehydes, O-protected / Hydrocyanation

ON THE STERIC COURSE OF THE ADDITION OF SOME ORGANOMETALLIC REAGENTS TO (R)-2,3-ISOPROPYLIDENE GLYCERALDEHYDE. SYNTHESIS OF OPTICALLY ACTIVE α-BENZYLOXY ALDEHYDES, ALCOHOLS, CARBOXYLIC ACIDS AND 1,2-DIOLS.

Organo-titanium and organo-zinc reagents were added stereoselectively to (R)-2,3-isopropylidene glyceraldehyde (1) to give the alcohols 2/3, which were converted into the optically active derivatives 4-11.