13136-54-4Relevant academic research and scientific papers
Enantioselective protonation of α-hetero carboxylic acid-derived ketene disilyl acetals under chiral ionic Bronsted acid catalysis
Uraguchi, Daisuke,Kizu, Tomohito,Ohira, Yuki,Ooi, Takashi
, p. 13489 - 13491 (2015/01/09)
Highly enantioselective protonation of α-halo and alkoxy carboxylic acid-derived ketene disilyl acetals is achieved by using P-spiro chiral diaminodioxaphosphonium barfate as a Bronsted acid catalyst, where the enantiofacial discrimination by the catalyst mainly stems from the recognition of the electronic difference between two substituents on the ketene disilyl acetal.
A new approach for the determination of the absolute configuration of secondary alcohols by 1H NMR with O-substituted mandelate derivatives
Chataigner, Isabelle,Lebreton, Jacques,Durand, Didier,Guingant, Andre,Villieras, Jean
, p. 1759 - 1762 (2007/10/03)
It is shown that the cheap and easily prepared mandelic acid esters (or their OAc analogues) are best suited than the expensive, although usually employed. OMe mandelic acid esters to assess both the enantiomeric excesses and absolute configurations of se
EASY AND GENERAL METHOD TO SYNTHESIZE CHIRAL 2-HYDROXYACID BENZOATES
Martin, V. S.,Nunez, M. T.,Tonn, C. E.
, p. 2701 - 2702 (2007/10/02)
The synthesis of 2-hydroxyacid benzoates, with high yields and excellent enantioselectivity, by regioselective opening of chiral 2,3-epoxyalcohols and ruthenium dioxide oxidation, is described.
ON THE STERIC COURSE OF THE ADDITION OF SOME ORGANOMETALLIC REAGENTS TO (R)-2,3-ISOPROPYLIDENE GLYCERALDEHYDE. SYNTHESIS OF OPTICALLY ACTIVE α-BENZYLOXY ALDEHYDES, ALCOHOLS, CARBOXYLIC ACIDS AND 1,2-DIOLS.
Mulzer, Johann,Angermann, Alfred
, p. 2843 - 2846 (2007/10/02)
Organo-titanium and organo-zinc reagents were added stereoselectively to (R)-2,3-isopropylidene glyceraldehyde (1) to give the alcohols 2/3, which were converted into the optically active derivatives 4-11.
